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Three Dimensional PET/MRI Images in OCD and Schizophrenia

Published online by Cambridge University Press:  07 November 2014

Monte S. Buchsbaum ,
Jacqueline Spiegel-Cohen  and
Tsechung Wei
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Abstract

Functional brain-imaging studies have suggested an opposite pattern of brain activity in obsessive-compulsive disorder (OCD) and schizophrenia. Patients with OCD have higher than normal activity in the frontal lobe and caudate nucleus while patients with schizophrenia have lower than normal activity in these areas. Changes in the nature of the connections between the executive and impulse control regions of the frontal lobe and the basal ganglia might be involved in both illnesses. These findings are statistical in nature and involve structures of complex three-dimensional shapes. New technology for studying the function of these structures may be useful in exploring the relation of each structure to symptoms of specific disorders. This technology may also enable identification of anatomical and functional causes of individual differences in medication response.

Type
Feature Articles
Information
CNS Spectrums , Volume 2 , Issue 4: Schizophrenia & OCD: Divergence , April 1997 , pp. 26 - 31
Copyright
Copyright © Cambridge University Press 1997

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