With the increase of academic pressure, depression has gradually become one of the most important diseases in students, affecting students’ learning, life and physical health. As an innovative educational method, interactive teaching model of marketing has the potential to stimulate students’ interest and enhance their enthusiasm for learning, and can become an auxiliary means to relieve students’ depressive symptoms.

300 college students were selected as the research subjects, and were divided into the control group and the experimental group according to 150 people in each group. The control group was treated with traditional drug therapy, and the experimental group was treated with marketing interactive teaching model, emphasizing students’ interaction and practice. Hamilton Depression Scale (HAMD) and self-rating Depression Scale (SDS) were used to evaluate the depression status of students.

The results showed that the Hamilton Depression Scale score of the experimental group was significantly lower than that of the control group (P< 0.05), and the difference was statistically significant. The self-rating depression scale score of the experimental group decreased by 9.1 points on average, and that of the control group decreased by 4.6 points. Statistical analysis showed that the improvement of depressive symptoms in the experimental group was significantly higher than that in the control group (P< 0.001).

The results showed that the interactive teaching model of marketing had a positive effect on the treatment of depression, and could significantly reduce the symptoms of depression and anxiety of students.

The research of higher vocational education teaching reform in Jiangsu City Vocational College is based on the research of the teaching mode of “learning, doing, thinking, innovation” which integrates science and practice—Building a new Teaching Model of Marketing (11-YB-02).