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Factors That Impact Choice of Antidepressant Treatment in Medically Complex Patients

Published online by Cambridge University Press:  07 November 2014

Pedro Luis Dago
Pedro Luis Dago*
Affiliation:
Dr. Dago is assistant professor of psychiatry in the Department of Psychiatry and Behavioral Sciences at, the Feinberg School of Medicine of Northwestern University in Chicago.
*
Pedro Luis Dago, MD, assistant professor of psychiatry, Department of Psychiatry and Behavioral Sciences, Feinberg School of Medicine of Northwestern University, 446 East Ontario Avenue, Chicago, IL 60611-3008; Tel: 312-695-2608; Fax: 312-695-5010; E-mail: PDago@nmff.org.
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Abstract

In medically complex patients with multiple comorbid illnesses who require concomitant medications, selecting the optimal antidepressant (ie, low risk of adverse effects and/or pharmacokinetic interactions) for an individual patient is critical for positive long-term patient outcomes. The serotonin-norepinephrine reuptake inhibitors (SNRIs) are increasingly being used as first-line treatment for major depressive disorder (MDD) and may prove beneficial for treatment of medically complex patients. Thus, it is key for clinicians to evaluate the differences in the pharmacokinetic and tolerability profiles of the SNRI class of antidepressants, evaluating differences both within the class and compared with other antidepressants used to treat MDD.

Type
Research Article
Information
CNS Spectrums , Volume 14 , Issue S12 , 2009 , pp. 20 - 27
Copyright
Copyright © Cambridge University Press 2009

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