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Comparison of the antimicrobial and antioxidant properties of halloysite nanotubes and organoclays as green source materials

Published online by Cambridge University Press:  24 January 2024

Nevin Çankaya Open the ORCID record for Nevin Çankaya [Opens in a new window] ,
Arzu Ünal Open the ORCID record for Arzu Ünal [Opens in a new window]  and
Safiye Elif Korcan Open the ORCID record for Safiye Elif Korcan [Opens in a new window]
Nevin Çankaya*
Affiliation:
Vocational School of Health Services, Usak University, Usak, Türkiye
Arzu Ünal
Affiliation:
Faculty of Agriculture, Department of Agricultural, Biotechnology, Iğdır University, Iğdır, Türkiye
Safiye Elif Korcan
Affiliation:
Vocational School of Health Services, Usak University, Usak, Türkiye
*
Corresponding author: Nevin Çankaya; Email: nevin.cankaya@usak.edu.tr
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Abstract

The antibacterial, antifungal and antioxidant effects of halloysite nanoclay, Cloisite 10A (C10A) and Cloisite 15A (C15A) organonanoclays were examined in this study. The antimicrobial action was assessed using the agar-well method and the disc diffusion method. The free radical-scavenging effects of the clays were determined using the 2,2-diphenyl-1-picrylhydrazyl method. Halloysite showed antimicrobial activity against Pseudomonas aeruginosa, Enterococcus faecalis and Staphylococcus aureus. C10A was effective against both Gram-positive bacteria (S. aureus, Listeria monocytogenes, Bacillus subtilis and E. faecalis) and Gram-negative bacteria (Escherichia coli, Klebsiella pneumoniae and P. aeruginosa). Additionally, only C10A was found to have an antimicrobial effect on Candida glabrata of 18 mm amongst the tested clays. C15A showed an antimicrobial effect on S. aureus and K. pneumoniae. It was determined that the antifungal properties of organoclays were higher than those of halloysite. The most effective clay type was determined to be C10A. The positively charged inner surface of the halloysite nanoclay can provide a large area to which negatively charged free radicals can attach. The modified C15A used in this study has two long-chain alkyl groups attached, whereas the modified C10A has a single long-chain alkyl group and a benzyl group attached. It is proposed that the differences in these antimicrobial effects are due to the structures of the molecules. According to these results, organoclays as green source materials could be used as additives and coatings in food processing, biomedical devices, filters and paints due to their antimicrobial and antioxidant properties.

Keywords

Antibacterialantifungalantioxidanthalloysiteorganoclay
Type
Article
Information
Clay Minerals , Volume 59 , Issue 1 , March 2024 , pp. 1 - 10
Copyright
Copyright © The Author(s), 2024. Published by Cambridge University Press on behalf of The Mineralogical Society of the United Kingdom and Ireland

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Footnotes

Associate Editor: Chunhui Zhou

References

Baschieri, A., Amorati, R., Benelli, T., Mazzocchetti, L., D'Angelo, E. & Valgimigli, L. (2019) Enhanced antioxidant activity under biomimetic settings of ascorbic acid included in halloysite nanotubes. Antioxidants, 8, 30.CrossRefGoogle ScholarPubMed
Biemer, J.J. (1973) Antimicrobial susceptibility testing by the Kirby–Bauer disc diffusion method. Annals of Clinical Laboratory Science, 3, 135–140.Google ScholarPubMed
Carcelli, M., Mazza, P., Pelizzi, C, Pelizzi, G. & Zani, F. (1995) Antimicrobial and genotoxic activity of 2,6-diacetylpyridinebis (acylhydrazones) and their complexes with some first transition series metal ions. X-ray crystal structure of a dinuclear copper (II) complex. Journal of Inorganic Biochemistry, 57, 43–62.CrossRefGoogle Scholar
Chapman, J.S. (2003) Biocide resistance mechanisms. International Biodeterioration & Biodegradation. 51, 133–138.CrossRefGoogle Scholar
Chauret, C.P. (2014) Sanitization. Pp. 360–364 in: Encyclopedia of Food Microbiology (Batt, C.A. & Tortorello, M.L., editors). Elsevier, Amsterdam, The Netherlands.CrossRefGoogle Scholar
Çankaya, N. & Sahın, R. (2019) Chitosan/clay bionanocomposites: structural, antibacterial, thermal and swelling properties. Cellulose Chemistry and Technology, 53, 537–549.CrossRefGoogle Scholar
Çankaya, N., Azarkan, S.Y. & Özek, N.T. (2021a) Preparation of poly(MPAEMA)/halloysite nanocomposites and investigation of antiproliferative activity. Journal of the Mexican Chemical Society, 65, 189–201.CrossRefGoogle Scholar
Çankaya, N., Vurgun, B. & Yalçın, S. (2021b) Antiproliferative effect of organoclay, poly(NCA) and their nanocomposites on HeLa cell line. Polymer Bulletin, 78, 7325–7335.CrossRefGoogle Scholar
Denyer, S.P. (1995) Mechanisms of action of antibacterial biocides. International Biodeterioration & Biodegradation, 36, 227–245.CrossRefGoogle Scholar
Deshmukh, R.K., Kumar, L. & Gaikwad, K.K. (2023) Halloysite nanotubes for food packaging application: a review. Applied Clay Science, 234, 106856.CrossRefGoogle Scholar
Ding, X., Wang, H., Chen, W., Liu, J. & Zhang, Y. (2014) Preparation and antibacterial activity of copper nanoparticle/halloysite nanotube nanocomposites via reverse atom transfer radical polymerization. Royal Society Chemistry, 4, 41993–41996.Google Scholar
Duan, L., Zhao, Q., Liu, J. & Zhang, Y. (2015) Antibacterial behavior of halloysite nanotubes decorated with copper nanoparticles in a novel mixed matrix membrane for water purification. Environmental Science: Water Research Technology, 1, 874–881.Google Scholar
Feng, Y., Luo, X., Li, Z., Fan, X., Wang, Y., He, R. & Liu, M. (2023a) A ferroptosis-targeting ceria anchored halloysite as orally drug delivery system for radiate on colitis therapy. Nature Communications, 14, 5083.CrossRefGoogle ScholarPubMed
Feng, Y., Zhang, D., Chen, X., Zhou, C. & Liu, M. (2023b) Confined-synthesis of ceria in tubular nanoclays for UV protection and anti-biofilm application. Advanced Functional Materials. Epub ahead of print. DOI: 10.1002/adfm.202307157.CrossRefGoogle Scholar
Gilbert, P. & Moore, L.E. (2005) Cationic antiseptics: diversity of action under a common epithet. Journal of Applied Microbiology, 99, 703–715.CrossRefGoogle Scholar
Haiwei, J., Hanjun, S. & Xiaogang, Q. (2016) Antibacterial applications of graphene-based nanomaterials: recent achievements and challenges. Advanced Drug Delivery, 105, 176–189.Google Scholar
Haydel, S.E., Remenih, C.M. & Williams, L.B. (2008) Broad-spectrum in vitro antibacterial activities of clay minerals against antibiotic-susceptible and antibiotic-resistant bacterial pathogens. Journal of Antimicrobial Chemotherapy, 61, 353–361.CrossRefGoogle ScholarPubMed
Hu, C.H. & Xia, M.S. (2006) Adsorption and antibacterial effect of copper-exchanged montmorillonite on Escherichia coli K88. Applied Clay Science, 31, 180–184.CrossRefGoogle Scholar
Isik, K. & Özdemir-Kocak, F. (2009) Antimicrobial activity screening of some sulfonamide derivatives on some Nocardia species and isolates. Microbiological Research, 164, 49–58.CrossRefGoogle ScholarPubMed
Jennings, M.C., Minbiole, K.P.C. & Wuest, W.M. (2015) Quaternary ammonium compounds: an antimicrobial mainstay and platform for innovation to address bacterial resistance. ACS Infectious Disease, 1, 288–303.CrossRefGoogle ScholarPubMed
Jo, S.C., Rim, A.R., Park, H.J., Yuk, H.G. & Lee, S.C. (2007) Combined treatment with silver ions and organic acid enhances growth-inhibition of Escherichia coli O157:H7. Food Control, 18, 1235–1240.CrossRefGoogle Scholar
Kamble, R., Ghag, M., Gaikawad, S. & Panda, B.K. (2012) Halloysite nanotubes and applications: a review. Journal of Advanced Scientific Research, 3, 25–29.Google Scholar
Korcan, S.E., Kayhan, R., Ünal, A. & Jahan, I. (2021) Determination of antimicrobial effects of western central Anatolian Three Ahlat species. Afyon Kocatepe University Journal of Sciences and Engineering, 21, 250–256.Google Scholar
Kumar, L., Deshmukh, R.K., Hakim, L. & Gaikwad, K.K. (2024) Halloysite nanotube as a functional material for active food packaging application: a review. Food and Bioprocess Technology, 17, 33–46.CrossRefGoogle Scholar
Lee, M.H., Kim, S.Y. & Park, H.J. (2018) Effect of halloysite nanoclay on the physical, mechanical, and antioxidant properties of chitosan films incorporated with clove essential oil. Food Hydrocolloids, 84, 58–67.CrossRefGoogle Scholar
Liu, M., Huang, J. & Huang, M. (2023) The environmental toxicity of halloysite clay and its composites. Pp. 559–574 in: Clay Composites: Advances in Material Research and Technology (Vithanage, M., Lazzara, G. & Rajapaksha, A.U., editors). Springer, Singapore.CrossRefGoogle Scholar
Maillard, J.-Y. (2002) Bacterial target sites for biocide action. Journal of Applied Microbiology, 92, 16–27.CrossRefGoogle ScholarPubMed
Massaro, M., Lazzara, G, Noto, R. & Riela, S. (2020). Halloysite nanotubes: a green resource for materials and life sciences. Rendiconti Lincei. Scienze Fisiche e Naturali, 31, 213–221.CrossRefGoogle Scholar
Meirelles, L.M.A. & Raffin, F.N. (2017) Clay and polymer-based composites applied to drug release: a scientific and technological prospection. Journal of Pharmacy & Pharmaceutical Sciences, 20, 115–134.CrossRefGoogle ScholarPubMed
Meng, N., Zhou, N.L., Zhang, S.Q. & Shen, J. (2009) Synthesis and antimicrobial activities of polymer/montmorillonite–chlorhexidine acetate nanocomposite films. Applied Clay Science, 42, 667–670.CrossRefGoogle Scholar
Nastasi, J.R., Kontogiorgos, V., Daygon, V.D. & Fitzgerald, M.A. (2022) Pectin-based films and coatings with plant extracts as natural preservatives: a systematic review. Trends in Food Science & Technology, 120, 193–211.CrossRefGoogle Scholar
Saadat, S., Pandey, G., Tharmavaram, M., Braganza, V. & Rowtani, D. (2020) Nano-interfacial decoration of halloysite nanotubes for the development of antimicrobial nanocomposites. Advances in Colloid and Interface Science, 275, 102063.CrossRefGoogle ScholarPubMed
Shchukin, D., Price, R., Sukhorukov, G. & Lvov, Y. (2005) Halloysite nanotubes as biomimetic nanoreactors. Small, 5, 510–513.CrossRefGoogle Scholar
Shu, Z., Yi, Z. Ouyyang, J. & Yang, H. (2017) Characterization and synergetic antibacterial properties of ZnO and CeO2 supported by halloysite. Applied Surface Science, 420, 833–838.CrossRefGoogle Scholar
Silva, F.C., Lima, L.C.B., Honório, L.M.C., Trigueiro, P., Osajima, J.A., Lobo, A.O. & Filho, E.C.S. (2019) Clays as biomaterials in controlled drug release: a scientific and technological short review. Biomedical Journal of Scientific & Technical Research, 15, 11237–11242.Google Scholar
Srivastava, A.K. & Dwivedi, K.N. (2018) Formulation and characterization of copper nanoparticles using Nerium odorum Soland leaf extract and its antimicrobial activity. International Journal of Drug Development and Research, 10, 29–34.Google Scholar
Sun, B., Xi, Z., Wu, F., Song, S., Huang, X, Chu, X. et al. (2019) Quaternized chitosan-coated montmorillonite interior antimicrobial metal–antibiotic in situ coordination complexation for mixed infections of wounds. Langmuir, 35, 15275–15286.CrossRefGoogle ScholarPubMed
Tong, G., Yulong, M., Peng, G. & Zirong, X. (2005) Antibacterial effects of the Cu(II)-exchanged montmorillonite on Escherichia coli K88 and Salmonella choleraesuis. Veterinary Microbiology, 105, 113–122.CrossRefGoogle ScholarPubMed
Uchida, M. (1995) Antimicrobial zeolite and its application. Chemistry & Industry, 46, 48–54.Google Scholar
Vieira, D.B. & Carmona-Ribeiro, A.M. (2006) Cationic lipids and surfactants as antifungal agents: mode of action. Journal of Antimicrobial Chemotherapy, 58, 760–767.CrossRefGoogle ScholarPubMed
Villano, D., Fernandez-Pachon, M.S., Moya, M.L., Troncoso, A.M. & Garcıa-Parrilla, M.C. (2007) Radical scavenging ability of polyphenolic compounds towards DPPH free radical. Talanta, 7, 230–235.CrossRefGoogle Scholar
Wang, J., Li, J.X., Ren, L., Zhao, A.S., Li, P., Leng, Y.X. et al. (2007) Antibacterial activity of silver surface modified polyethylene terephthalate by filtered cathodic vacuum arc method. Surface and Coatings Technology, 201, 6893–6896.CrossRefGoogle Scholar
Williams, L.B. & Haydel, S.E. (2010) Evaluation of the medicinal use of clay minerals as antibacterial agents. International Geology Review, 52, 745–770.CrossRefGoogle ScholarPubMed
Williams, L.B., Haydel, S.E., Giese, R.F. & Eberl, D.D. (2008) Chemical and mineralogical characteristics of French green clays used for healing. Clays and Clay Minerals, 56, 437–452.CrossRefGoogle ScholarPubMed
Ying, G.G. (2006) Fate, behavior and effects of surfactants and their degradation products in the environment. Environment International, 32, 417–431.CrossRefGoogle ScholarPubMed
Yue, X., Yang, X., Li, H., Zhang, R. & Qin, D. (2019) Quaternary ammonium compounds-modified halloysite and its antifungal performance. Pp. 121–131 in: Physics and Techniques of Ceramic and Polymeric Materials (Han, Y., editor). Springer Proceedings in Physics 216. Springer, Singapore.CrossRefGoogle Scholar
Zhang, Y., Giurleo, D., Parhi, A., Kaul, M., Pilch, D.S. & LaVoie, E.J. (2013) Substituted 1,6-diphenlnaphthalenes as FtsZ-targeting antibacterial agents. Bioorganic & Medicinal Chemistry Letters, 23, 2001–2006.CrossRefGoogle ScholarPubMed
Zhao, P., Feng, Y., Zhou, Y., Tan, C. & Liu, M. (2023) Gold@halloysite nanotubes–chitin composite hydrogel with antibacterial and hemostatic activity for wound healing. Bioactive Materials, 20, 355–367.CrossRefGoogle ScholarPubMed
Zhao, X., Wan, Q., Fu, X., Meng, X., Ou, X., Zhong, R. et al. (2019) Toxicity evaluation of one-dimensional nanoparticles using Caenorhabditis elegans: a comparative study of halloysite nanotubes and chitin nanocrystals, ACS Sustainable Chemistry & Engineering, 7, 18965–18975.CrossRefGoogle Scholar
Zhong, B., Lin, J., Liu, M., Jia, Z., Luo, Y. & Jia, D.F.L. (2017) Preparation of halloysite nanotubes loaded antioxidant and its antioxidative behaviour in natural rubber. Polymer Degradation & Stability, 141, 19–25.CrossRefGoogle Scholar