Hostname: page-component-848d4c4894-75dct Total loading time: 0 Render date: 2024-04-30T12:23:23.244Z Has data issue: false hasContentIssue false

Successful treatment of the focal ectopic atrial tachycardia in an infant with a single dose of ivabradin

Published online by Cambridge University Press:  24 March 2023

Oguzhan Gul*
Affiliation:
Department of Pediatric Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Research and Education Hospital, Istanbul, Turkey
Hasan Candas Kafali
Affiliation:
Department of Pediatric Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Research and Education Hospital, Istanbul, Turkey
Yakup Ergul
Affiliation:
Department of Pediatric Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Research and Education Hospital, Istanbul, Turkey
*
Author for correspondence: Department of Pediatric Cardiology, İstanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Research and Education Hospital, Istanbul, Turkey. E-mail: droguzkaan80@hotmail.com

Abstract

We report on a 12-month-old boy with an ectopic atrial tachycardia successfully treated with the ivabradine that acts on cardiac pacemaker cells by selectively inhibiting the If channel. The patient was diagnosed with supraventricular tachycardia in another centre, and multi-drug therapy was unsuccessful to restore sinus ryhthm, so he was sent to our hospital for catheter ablation. We stopped the medications the patient was taking and started using ivabradine. Sinus rhythm was restored 2 hours after ivabradine treatment was started.

Type
Brief Report
Copyright
© The Author(s), 2023. Published by Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Gillette, PC. The mechanisms of supraventricular tachycardia in children. Circulation 1976; 54: 133139. DOI 10.1161/01.CIR.54.1.133.CrossRefGoogle ScholarPubMed
Koike, K, Hesslein, PS, Finlay, CD, Williams, WG, Izukawa, T, Freedom, RM. Atrial automatic tachycardia in children. Am J Cardiol. 1988; 61: 11271130.CrossRefGoogle ScholarPubMed
January, CT, Wann, LS, Calkins, H, et al. 2019 AHA/ACC/HRS focused update of the 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society in Collaboration With the Society of Thoracic Surgeons. Circulation 2019; 140: e125e151.CrossRefGoogle Scholar
Banavalikar, B, Shenthar, J, Padmanabhan, D, et al. Clinical and electrophysiological correlates of ıncessant ıvabradine-sensitive atrial tachycardia. Circ Arrhythm Electrophysiol 2019; 12: e007387. DOI 10.1161/CIRCEP.119.007387.CrossRefGoogle ScholarPubMed
Dieks, JK, Klehs, S, Müller, MJ, Paul, T, Krause, U. Adjunctive ivabradine in combination with amiodarone: a novel therapy for pediatric congenital junctional ectopic tachycardia. Heart Rhythm 2016; 13: 12971302. DOI 10.1016/j.hrthm.2016.03.015.CrossRefGoogle ScholarPubMed
Ergul, Y, Ozturk, E, Ozgur, S, Ozyurt, A, Cilsal, E, Guzeltas, A. Ivabradine is an effective antiarrhythmic therapy for congenital junctional ectopic tachycardia-induced cardiomyopathy during infancy: case studies. Pacing Clin Electrophysiol 2018; 41: 13721377. DOI 10.1111/pace.13402.CrossRefGoogle ScholarPubMed
Kang, KT, Etheridge, SP, Kantoch, MJ, et al. Current management of focal atrial tachycardia in children: a multicenter experience. Circ Arrhythm Electrophysiol. 2014; 7: 664670.CrossRefGoogle ScholarPubMed
Michel, H, Heißenhuber, F, Wellmann, S, Melter, M, Gerling, S. Ectopic atrial tachycardia in a 12-month-old girl treated with ıvabradine and beta-blocker, a case report. Pediatr Cardiol 2020; 8. DOI 10.3389/fped.2020.00313.Google Scholar
Karmegaraj, B, Balaji, S, Raju, PN, et al. Tachycardia-induced cardiomyopathy secondary to incessant ectopic atrial tachycardia in two infants: potential new indication for early initiation of enteral ivabradine. Ann Pediatr Cardiol 2021; 14: 422427.CrossRefGoogle ScholarPubMed
Janson, M, Tan, RB, Iyer, R, Vogel, RL, Vetter, VL, Shah, MJ. Ivabradine for treatment of tachyarrhythmias inchildren and young adults. HeartRhythm Case Rep 2019; 5: 333337. DOI 10.1016/j.hrcr.2019.03.007 eCollection 2019 Jun.CrossRefGoogle Scholar