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Self- and informant-reported executive function in young adults operated for atrial or ventricular septal defects in childhood

Published online by Cambridge University Press:  07 January 2022

Yasmin S. El Dabagh Open the ORCID record for Yasmin S. El Dabagh [Opens in a new window] ,
Benjamin Asschenfeldt Open the ORCID record for Benjamin Asschenfeldt [Opens in a new window] ,
Benjamin Kelly ,
Lars Evald  and
Vibeke E. Hjortdal
Yasmin S. El Dabagh*
Affiliation:
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Aarhus, Denmark
Benjamin Asschenfeldt
Affiliation:
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Aarhus, Denmark
Benjamin Kelly
Affiliation:
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark Department of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Aarhus, Denmark
Lars Evald
Affiliation:
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark Hammel Neurorehabilitation Center, University Research Clinic, Hammel, Denmark
Vibeke E. Hjortdal
Affiliation:
Department of Cardiothoracic Surgery, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark Institute of Clinical Medicine, Copenhagen University, Copenhagen, Denmark
*
Author for correspondence: Y. S. El Dabagh, Department of Clinical Medicine, Aarhus University, Palle Juul-Jensens Boulevard 82, Aarhus 8200, Denmark. Tel: 61717936. E-mail: yasmin.eldabagh@clin.au.dk
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Abstract

Background:

Adults with simple congenital heart defects (CHD) have increased risk of neurodevelopmental challenges including executive dysfunction. It is unknown if the executive dysfunction is universal or if it is driven by dysfunction in specific clinical subscales and how it might affect psychosocial aspects of everyday life.

Methods:

The self-reported and informant-reported executive function of adults with an average age of 26 ± 5 (range 18–41) who underwent childhood surgery for atrial septal defects (n = 34) or ventricular septal defects (n = 32) and matched controls (n = 40) were evaluated using the Behavior Rating Inventory of Executive Functions - Adult version (BRIEF-A).

Results:

The CHD group reported having more executive dysfunction than controls in all BRIEF-A clinical subscales (p < 0.020) and more than their informants reported on their behalf (p < 0.006). The CHD group had received three times more special teaching (44% compared to 16%) and pedagogical psychological counselling (14% compared to none) and had a three times higher occurrence of psychiatric disorders than controls (33% compared to 11%). Lower educational levels and psychiatric disorders were associated with higher BRIEF-A scores (p < 0.03).

Conclusions:

Adults operated for septal defects in childhood report more challenges with all aspects of the executive functions than controls and more than relatives are aware of.

Keywords

Atrial septal defectventricular septal defectsimple CHDexecutive functionneurodevelopment
Type
Original Article
Information
Cardiology in the Young , Volume 32 , Issue 12 , December 2022 , pp. 1917 - 1924
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Copyright
© The Author(s), 2022. Published by Cambridge University Press

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