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The impact of physical activity changes on exercise capacity and health-related quality of life in young patients with CHD: a 3-year follow-up study

Published online by Cambridge University Press:  11 December 2023

Hyun Jeong Kim
Affiliation:
Department of Sport Science, University of Seoul, Seoul, South Korea
Ja-kyoung Yoon
Affiliation:
Department of Pediatrics, Sejong General Hospital, Bucheon, South Korea
Min Jeong Cho
Affiliation:
Department of Sport Science, University of Seoul, Seoul, South Korea
Setor K. Kunutsor
Affiliation:
Leicester Real World Evidence Unit, Diabetes Research Centre, University of Leicester, Leicester General Hospital, Leicester, UK
Seong-Ho Kim
Affiliation:
Department of Pediatrics, Sejong General Hospital, Bucheon, South Korea
Sae Young Jae*
Affiliation:
Department of Sport Science, University of Seoul, Seoul, South Korea
*
Corresponding author: Sae Young Jae; Email: syjae@uos.ac.kr

Abstract

Objective:

This study examined the relationship between changes in physical activity and their impact on exercise capacity and health-related quality of life over a 3-year span in patients with CHD.

Methods:

We evaluated 99 young patients with CHD, aged 13–18 years at the outset. Physical activity, health-related quality of life, and exercise capacity were assessed via questionnaires and peak oxygen uptake measurements at baseline and after 3 years; changes in measures were estimated between the two time points and categorised into quartiles. Participants were stratified according to achieved (active) or not-achieved (inactive) recommended levels of physical activity (≥150 minutes/week) at both time points.

Results:

Despite increases in physical activity, exercise capacity, and health-related quality of life over 3 years, the changes were not statistically significant (all p > 0.05). However, a positive association was found between physical activity changes and exercise capacity (ß = 0.250, p = 0.040) and health-related quality of life improvements (ß = 0.380, p < 0.001). Those with the most pronounced physical activity increase showed notable exercise capacity (p < 0.001) and health-related quality of life increases (p < 0.001) compared with patients with the largest decline in physical activity. The active-inactive category demonstrated a notable decline in exercise capacity compared to the active-active group, while the inactive-active group showed health-related quality of life improvements.

Conclusions:

Over 3 years, increased physical activity was consistently linked to increases in exercise capacity and health-related quality of life in patients with CHD, highlighting the potential of physical activity augmentation as an intervention strategy.

Type
Original Article
Copyright
© The Author(s), 2023. Published by Cambridge University Press

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Footnotes

Hyun Jeong Kim and Ja-kyoung Yoon contributed equally to this work as co-first authors of this manuscript.

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