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Epidemiologic study of patients after Fontan operation based on Medical Aid Program for Chronic Pediatric Diseases of Specified Categories cohort

Published online by Cambridge University Press:  09 June 2022

Takanari Fujii Open the ORCID record for Takanari Fujii [Opens in a new window] ,
Akinori Moriichi ,
Naoko Kakee ,
Hitoshi Kato  and
Hideshi Tomita
Takanari Fujii*
Affiliation:
Pediatric Heart Disease and Adult Congenital Heart Disease Center, Showa University Hospital, Tokyo, Japan
Akinori Moriichi
Affiliation:
Division of Information for Specific Pediatric Chronic Diseases, Research Institute, National Center for Child Health and Development, Tokyo, Japan
Naoko Kakee
Affiliation:
Division of Information for Specific Pediatric Chronic Diseases, Research Institute, National Center for Child Health and Development, Tokyo, Japan
Hitoshi Kato
Affiliation:
Department of Pediatric Cardiology, National Center for Child Health and Development, Tokyo, Japan
Hideshi Tomita
Affiliation:
Pediatric Heart Disease and Adult Congenital Heart Disease Center, Showa University Hospital, Tokyo, Japan
*
Author for correspondence: Takanari Fujii, MD, PhD, Pediatric Heart Disease and Adult Congenital Heart Disease Center, Showa University Hospital, 1-5-8 Hatanodai, Shinagawa-Ku, Tokyo, 142-8666, Japan. Tel: +81-3-3784-8000; Fax: +81- 3-3784-8714 7. E-mail: takanari@nn.iij4u.or.jp
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Abstract

Nationwide registry data of patients with single-ventricle physiology have been rarely reported. The Medical Aid Program for Chronic Pediatric Diseases of Specified Categories (Japan) has contributed to the financial support of medical expense for patients younger than 20 years with chronic paediatric disease, and almost all children in Japan who require disease-specific treatment voluntarily apply to this programme. The epidemiology and medium- to long-term outcome of patients following a Fontan procedure were investigated using the database. The usefulness of this epidemiologic investigation in identifying real-world objectives and clinical applications was also examined. A total of 2862 patients who underwent a Fontan operation were identified from 18,589 patients with chronic heart disease registered to the medical aid programme. The details of symptoms, treatment, and somatic growth were evaluated, from which we were able to clarify the nationwide data regarding the current status of post-Fontan patients younger than 20 years. This study elucidated the current status of post-Fontan patients under 20 years of age in Japan. Data analysis of the Medical Aid Program for Chronic Pediatric Diseases of Specified Categories cohort provided useful information towards understanding the comprehensive status of patients with chronic heart disease and contributed to improved disease management.

Keywords

CHDepidemiologyFontan operationsingle-ventricle physiology
Type
Original Article
Information
Cardiology in the Young , Volume 33 , Issue 2 , February 2023 , pp. 248 - 254
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Copyright
© The Author(s), 2022. Published by Cambridge University Press

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