Hostname: page-component-848d4c4894-v5vhk Total loading time: 0 Render date: 2024-07-01T10:19:25.387Z Has data issue: false hasContentIssue false
  • English
  • Français

Co-occurring Duchenne muscular dystrophy and hypertrophic cardiomyopathy in an adult with atypical cardiac phenotype

Published online by Cambridge University Press:  29 January 2014

Animesh Tandon ,
Michael D. Taylor  and
Linda H. Cripe
Animesh Tandon*
Affiliation:
The Heart Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America
Michael D. Taylor
Affiliation:
The Heart Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America
Linda H. Cripe
Affiliation:
The Heart Center, Nationwide Children’s Hospital, Columbus, Ohio, United States of America
*
Correspondence to: Dr A. Tandon, MD, The Heart Institute, Cincinnati Children’s Hospital Medical Center, 3333 Burnet Ave MLC 2003, Cincinnati, OH 45229-3026, United States of America. Tel: +1 513 636 4274; Fax: +1 513 636 3952; E-mail: animesh.tandon@cchmc.org
Get access Rights & Permissions [Opens in a new window]

Abstract

We present the case of a 29-year-old man with mutation-positive Duchenne muscular dystrophy and mutation-positive hypertrophic cardiomyopathy. His cardiac phenotype has characteristics of both disorders; he manifests sub-epicardial left ventricular free wall late gadolinium enhancement that is consistent with Duchenne cardiomyopathy, as well as asymmetric ventricular septal hypertrophy, hyperdynamic left ventricular systolic function, and septal mid-myocardial late gadolinium enhancement, which are characteristic of hypertrophic cardiomyopathy.

Keywords

Duchenne muscular dystrophyhypertrophic cardiomyopathycardiac magnetic resonance imaging
Type
Brief Reports
Information
Cardiology in the Young , Volume 25 , Issue 2 , February 2015 , pp. 355 - 357
Copyright
© Cambridge University Press 2014 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Frankel, KA, Rosser, RJ. The pathology of the heart in progressive muscular dystrophy: epimyocardial fibrosis. Hum Pathol 1976; 7: 375–386.Google Scholar
2. Puchalski, MD, Williams, RV, Askovich, B, et al. Late gadolinium enhancement: precursor to cardiomyopathy in Duchenne muscular dystrophy? Int J Cardiovasc Imaging 2009; 25: 57–63.Google Scholar
3. Rubinshtein, R, Glockner, JF, Ommen, SR, et al. Characteristics and clinical significance of late gadolinium enhancement by contrast-enhanced magnetic resonance imaging in patients with hypertrophic cardiomyopathy. Circ Heart Fail 2010; 3: 51–58.CrossRefGoogle ScholarPubMed
4. Park, OY, Ahn, Y, Park, WS, et al. Rapid progression from hypertrophic cardiomyopathy to heart failure in a patient with Becker’s muscular dystrophy. Eur J Heart Fail 2005; 7: 684–688.Google Scholar

Tandon Supplementary Material

Movie 1

Download Tandon Supplementary Material(Video)
Video 489 KB