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Breastfeeding does not protect against the development of carditis in children with acute rheumatic fever

Published online by Cambridge University Press:  20 June 2022

Funda Gurbuz Open the ORCID record for Funda Gurbuz [Opens in a new window] ,
Nejla Canbulat Sahiner ,
Emin Unal ,
Ahmet Seyfeddin Gurbuz  and
Tamer Baysal
Funda Gurbuz*
Affiliation:
Department of Nursing, Karamanoglu Mehmetbey University Health Sciences Institute, Karaman, Turkey
Nejla Canbulat Sahiner
Affiliation:
Department of Nursing, Karamanoglu Mehmetbey University Health Sciences Institute, Karaman, Turkey
Emin Unal
Affiliation:
Department of Pediatric Cardiology, Necmettin Erbakan University, Meram Medicine Faculty, Konya, Turkey
Ahmet Seyfeddin Gurbuz
Affiliation:
Department of Cardiology, Necmettin Erbakan University, Meram Medicine Faculty, Konya, Turkey
Tamer Baysal
Affiliation:
Department of Pediatric Cardiology, Necmettin Erbakan University, Meram Medicine Faculty, Konya, Turkey
*
Author for correspondence: Funda Gurbuz, Department of Nursing, Karamanoglu Mehmetbey University Health Sciences Institute, Karaman, Turkey. Tel: +90 332 223 6000, +905065005321; Fax: +90 332 2236181. E-mail: fundakaya033@gmail.com
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Abstract

Introduction:

Acute rheumatic fever is an autoimmune disease that develops due to streptococcal infection. The positive effect of breastfeeding on the development of the child’s immune system is well documented. In this study, we aimed to investigate the effect of breast milk intake period on the development of carditis.

Materials and methods:

Patients (n: 182) who were diagnosed with acute rheumatic fever between 2010 and 2019 were enrolled in the study. The patients were divided into groups according to carditis development. The demographic, socio-economic, and breastfeeding data were compared between groups.

Results:

The mean age of the patients was 10.5 ± 3.4, and 43.4 % (n: 79) of them were female. Independent predictors of the development of carditis in the first acute rheumatic fever episode were the number of children at home (OR: 1.773, CI 95%: 1.105, 2.845; p: 0.018) and breast milk intake less than 6 months (OR: 0.404, CI 95%: 0.174, 0.934; p: 0.034). Independent predictors of the development of carditis in any of the acute rheumatic fever episodes were the number of children at home (OR: 1.858, CI 95%: 1.100, 3.137; p: 0.021) and female gender (OR: 3.504, CI 95%: 1.227, 10.008; p: 0.019). The only independently predictor of the development of chorea during acute rheumatic fever was female gender (OR: 3.801, CI 95%: 1.463, 9.874; p: 0.006).

Conclusion:

Although the occurrence of carditis is less common during the first acute rheumatic fever attack in patients with breast milk intake less than six months, this advantage is lost in recurrent attacks. This study showed that breast milk does not have a negative effect on acute rheumatic fever carditis.

Keywords

Acute rheumatic fevercarditisbreastfeedingimmune system
Type
Original Article
Information
Cardiology in the Young , Volume 33 , Issue 6 , June 2023 , pp. 899 - 903
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Copyright
© The Author(s), 2022. Published by Cambridge University Press

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