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Arrhythmias after surgical correction of complete transposition—follow-up into adolescence

Published online by Cambridge University Press:  19 August 2008

Paul A. Hutter ,
Menno W. Baars ,
Karin T. den Boer ,
Ronald F. F. van den Haak ,
Eric Harinck ,
J. Herre Kingma ,
Avram A. Benatar  and
Erik Jan Meijboom
Paul A. Hutter*
Affiliation:
From the Departments of Cardiology, Wilhelmina Children's Hospital, University of Utrecht, Utrecht
Menno W. Baars
Affiliation:
Departments of Cardiology, St. Antonius Hospital, Nieuwegein
Karin T. den Boer
Affiliation:
From the Departments of Cardiology, Wilhelmina Children's Hospital, University of Utrecht, Utrecht
Ronald F. F. van den Haak
Affiliation:
From the Departments of Cardiology, Wilhelmina Children's Hospital, University of Utrecht, Utrecht
Eric Harinck
Affiliation:
From the Departments of Cardiology, Wilhelmina Children's Hospital, University of Utrecht, Utrecht
J. Herre Kingma
Affiliation:
Departments of Cardiology, St. Antonius Hospital, Nieuwegein
Avram A. Benatar
Affiliation:
From the Departments of Cardiology, Wilhelmina Children's Hospital, University of Utrecht, Utrecht
Erik Jan Meijboom
Affiliation:
From the Departments of Cardiology, Wilhelmina Children's Hospital, University of Utrecht, Utrecht
*
Dr. Paul A. Hutter, Wilhelmina Children's Hospital. P O Box 18009, 3501 CA Utrecht, the Netherlands. Tel. 09-31-30-2320355; Fax. 09-31-30-2320710.
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Summary

The long-term natural progression of cardiac rhythm and the incidence of serious arrhythmias in relation to previous procedures and associated heart defects were studied in a group of 76 patients after an arterial switch operation for complete transposition and compared to a group of 24 patients who had undergone intraatrial corrections (Mustard or Senning operation). Standard and 24-hour ambulatory electrocardiograms were reviewed. Mean follow-up was 7.9 years (range 2-16) after an arterial switch and 15.2 years (range 6-26) following the Mustard or Senning procedures. One patient died after an arterial switch from pulmonary hypertension (age 9.9 years), and three patients died suddenly, presumably from arrhythmias, following atrial redirection procedures (ages 13, 18 and 20 years). Symptomatic arrhythmias were not seen after the arterial switch operation. Three patients required pacemaker implantation after atrial redirection, and a further two required medication to control tachyarrhythmias. Survival analysis of sequential electrocardiograms showed a mean maintenance of sinus rhythm during 12.9 years (95% confidence interval 11.4-14.5) after the arterial switch and 9.0 years (7.3-10.7) after atrial procedures (p=0.003). Development of heart rate was significantly different (p=0.001), with higher rates in adolescents after an arterial switch. Twenty-four-hour recordings were abnormal in five of 72 patients following arterial correction, disclosing excessive ventricular extrasystoles in four (three monomorphic, one polymorphic) and a wandering pacemaker in one. After atrial procedures, 11 of 19 were abnormal (p<0.001), with sinus or atrial bradycardia in eight, atrial flutter in two, and monomorphic ventricular tachycardias in one. Abnormal findings on either 12-lead or 24-hour electrocardiograms were seen in 22% of patients following an arterial switch procedure and 83% of patients undergoing atrial redirection (p<0.001). Sinus rhythm, therefore, is preserved longer and arrhythmias are less frequent and less severe after the arterial switch operation than after the Mustard or Senning operations.

Keywords

Complete transpositionarrhythmiasarterial switch operationMustard procedureSenning proceduresudden death
Type
Original Manuscripts
Information
Cardiology in the Young , Volume 6 , Issue 2 , April 1996 , pp. 156 - 161
Copyright
Copyright © Cambridge University Press 1996

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References

1.Ferencz, C, Rubin, JD, McCarter, RJ, Brenner, JI, Neill, CA, Perry, LW, Hepner, SI, Downing, JW. Congenital heart disease: Prevalence at livebirth. The Baltimore-Washington Infant Study. Am J Epidemiol 1985; 121: 31–36.CrossRefGoogle ScholarPubMed
2.Liebman, J, Cullum, L, Belloc, N. Natural history of transposition of the great arteries. Anatomy and birth and dead characteristics. Circulation 1969; 40: 237–262.CrossRefGoogle ScholarPubMed
3.Rashkind, WJ, Miller, WW. Creation of an atrial sepal defect without thoracotomy. J Am Med Assoc 1966; 196: 991–992.CrossRefGoogle Scholar
4.Tynan, M. Survival of infants with transposition of great arteries after balloon atrial septostomy. Lancet 1971; 1: 621–623.CrossRefGoogle ScholarPubMed
5.Mustard, WT. Successful two-stage correction of transposition of the great vessels. Surgery 1964; 55: 469–472.Google ScholarPubMed
6.Senning, A. Surgical correction of transposition of the great vessels. Surgery 1959; 45: 966–980.Google ScholarPubMed
7.Gillette, PC, Kugler, JD, Garson, A Jr, Gutgesell, HP, Duff, DF, McNamara, DG. Mechanisms of cardiac arrhythmias after the Mustard operation for transposition of the great arteries. Am J Cardiol 1980; 45: 1225–1230.CrossRefGoogle ScholarPubMed
8.Warnes, CA, Somerville, J. Transposition of the great arteries: late results in adolescents and adults after the Mustard procedure. Br Heart J 1987; 58: 148–155.CrossRefGoogle ScholarPubMed
9.Turina, MI, Siebenmann, R, von Segesser, L, Schönbeck, M, Senning, A. Late functional deterioration after atrial correction for transposition of the great arteries. Circulation 1989; 80 (Suppl I): 1162–1167.Google ScholarPubMed
10.Jatene, AD, Fontes, VF, Paulista, PP, Souza, LCB, Neger, F, Galantier, M, Sousa, JEMR. Successful anatomic correction of transposition of the great arteries. A preliminary report. Arg Bras Cardiol 1975; 28: 461–464.Google ScholarPubMed
11.Duster, MC, Bink-Boelkens, MThE, Wampler, D, Gillette, PC, McNamara, DG, Cooley, DA. Long-term follow-up of dysrhythmias following the Mustard procedure. Am Heart J 1985; 109: 1323–1326.CrossRefGoogle ScholarPubMed
12.Bink-Boelkens, MThE, Velvis, H, Van der Heide, JJ, Eygelaar, A, Hardjowijono, RA. Dysrhythmias after atrial surgery in children. Am Heart J 1983; 106: 125–130.CrossRefGoogle ScholarPubMed
13.Davignon, A, Rautaharju, P, Boisselle, E, Soumis, F, Mégélas, M, Choquette, A. Normal ECG standards for infants and children. Pediatr Cardiol 1979–80; 1: 133–152.CrossRefGoogle Scholar
14.Gewillig, M, Cullen, S, Mertens, B, Lasaffre, E, Deanfield, J. Risk factors for arrhythmia and death after Mustard operation for simple transposition of the great arteries. Circulation 1991; 84 (Suppl III): III187–III192.Google ScholarPubMed