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Acute rheumatic fever in south-east of Turkey: clinical features and epidemiological evaluation of the patients over the last 25 years

Published online by Cambridge University Press:  02 July 2020

Sevcan Erdem Open the ORCID record for Sevcan Erdem [Opens in a new window] ,
Fadli Demir Open the ORCID record for Fadli Demir [Opens in a new window] ,
Mustafa Ayana ,
Oguz Canan ,
Yankı Kaan Okuducu ,
Alev Arslan ,
Osman Kucukosmanoglu  and
Nazan Özbarlas
Sevcan Erdem*
Affiliation:
Department of Pediatric Cardiology, Faculty of Medicine, Çukurova University, Adana, Turkey
Fadli Demir
Affiliation:
Department of Pediatric Cardiology, Faculty of Medicine, Çukurova University, Adana, Turkey
Mustafa Ayana
Affiliation:
Department of Pediatrics, Faculty of Medicine, Çukurova University, Adana, Turkey
Oguz Canan
Affiliation:
Department of Pediatrics, Faculty of Medicine, Çukurova University, Adana, Turkey
Yankı Kaan Okuducu
Affiliation:
Faculty of Medicine, Çukurova University, Adana, Turkey
Alev Arslan
Affiliation:
Department of Pediatric Cardiology, Faculty of Medicine, Çukurova University, Adana, Turkey
Osman Kucukosmanoglu
Affiliation:
Department of Pediatric Cardiology, Faculty of Medicine, Çukurova University, Adana, Turkey
Nazan Özbarlas
Affiliation:
Department of Pediatric Cardiology, Faculty of Medicine, Çukurova University, Adana, Turkey
*
Author for correspondence: Sevcan ERDEM, MD, Department of Pediatric Cardiology, Medical Faculty, Balcali Hospital, Çukurova University, Saricam/Adana01330, Turkey. Tel: +905323378563; Fax: +90 322 338 68 32; E-mail: hserdem@gmail.com
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Abstract

This study evaluates clinical and epidemiological features of acute rheumatic fever using the data of last 25 years in our hospital in south-east of Turkey. The medical records of 377 patients with acute rheumatic fever admitted to Pediatric Cardiology Department of Çukurova University during 1993–2017 were retrospectively analysed. Two hundred and six patients were admitted between 1993 and 2000, 91 between 2001 and 2008, and 80 between 2009 and 2017. The largest age group (52%) were between 9 to 12 years of age and approximately two-thirds of the patients presented in the spring and winter seasons (62.8%). Among the major findings, the most common included carditis 83.6% (n = 315), arthritis at 74% (n = 279), Sydenham’s chorea at 13.5% (n = 51), and only two patients (0.5%) had erythema marginatum and two patients (0.5%) had subcutaneous nodule. Carditis was the most common manifestation observed in 315 patients (83.6%). The most commonly affected valve was the mitral valve alone (54.9%), followed by a combined mitral and aortic valves (34%) and aortic valve alone (5.7%). Of the patients with carditis, 48.6% (n = 153) had mild carditis, of which 45 had a subclinical. Sixty-two patients (19.7%) had moderate and 100 patients (31.7%) had severe carditis. At the follow-up, 2 patients died and 16 patients underwent valve surgery. Twenty-eight (7.4%) patients’ valve lesions were completely resolved. Conclusion: Although the incidence of acute rheumatic fever decreased, it still is an important disease that can cause serious increases in morbidity and mortality rates in our country.

Keywords

Acute rheumatic feverclinical presentationJones criteria
Type
Original Article
Information
Cardiology in the Young , Volume 30 , Issue 8 , August 2020 , pp. 1086 - 1094
Copyright
© The Author(s), 2020. Published by Cambridge University Press

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