Hostname: page-component-77c89778f8-sh8wx Total loading time: 0 Render date: 2024-07-24T18:29:37.999Z Has data issue: false hasContentIssue false

Wolff–Parkinson–White syndrome presenting with steroid-induced bradycardia in a patient with acute rheumatic fever

Part of: Infectious

Published online by Cambridge University Press:  02 August 2018

Ali Orgun
Affiliation:
Department of Pediatric Cardiology, Ankara Child Health and Diseases, Hematology Oncology Training and Research Hospital, University of Health Sciences, Ankara, Turkey
Hazım A. Gursu*
Affiliation:
Department of Pediatric Cardiology, Ankara Child Health and Diseases, Hematology Oncology Training and Research Hospital, University of Health Sciences, Ankara, Turkey
Ibrahim I. Cetin
Affiliation:
Department of Pediatric Cardiology, Ankara Child Health and Diseases, Hematology Oncology Training and Research Hospital, University of Health Sciences, Ankara, Turkey
*
Author for correspondence: A. H. Gursu, Associate Professor Department of Pediatric Cardiology, Ankara Child Health and Diseases, Hematology Oncology Training and Research Hospital, University of Health Sciences, 06110 Ankara, Turkey. Tel: +90 505 561 87 99; Fax: +09 312 347 23 30; E-mail: hagursu@yahoo.com.tr

Abstract

Steroids are used in the treatment of acute rheumatic fever with moderate-to-severe carditis. Corticosteroids have several cardiovascular side affects that are more common in adults than in children. Corticosteroid-related bradycardia is a rarely seen side effect. Children with bradycardia following oral corticosteroid use are rarely reported previously. We present a child who developed bradycardia after oral corticosteroid treatment and concurrent Wolff–Parkinson–White pattern.

Type
Brief Report
Copyright
© Cambridge University Press 2018 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Gewitz, MH, Baltimore, RS, Tani, LY, et al. Revision of the Jones criteria for the diagnosis of acute rheumatic fever in the era of Doppler echocardiography: a scientific statement from the American Heart Association. Circulation 2015; 131: 18061818.Google Scholar
2. Klein-Gitelman, MS, Pachman, LM. Intravenous corticosteroids: adverse reactions are more variable than expected in children. J Rheumatol 1998; 25: 19952002.Google Scholar
3. Taylor, MR, Gaco, D. Symptomatic sinus bradycardia after a treatment course of high-dose oral prednisone. J Emerg Med 2013; 45: e55e58.Google Scholar
4. Vasheghani-Farahani, A, Sahraian, MA, Darabi, L, Aghsaie, A, Minagar, A. Incidence of various cardiac arrhythmias and conduction disturbances due to high dose intravenous methylprednisolone in patients with multiple sclerosis. J Neurol Sci 2011; 309: 7578.Google Scholar
5. Kucukosmanoglu, O, Karabay, A, Ozbarlas, N, Noyan, A, Anarat, A. Marked bradycardia due to pulsed and oral methylprednisolone therapy in a patient with rapidly progressive glomerulonephritis. Nephron 1998; 80: 484.Google Scholar
6. Akikusa, JD, Feldman, BM, Gross, GJ, Silverman, ED, Schneider, R. Sinus bradycardia after intravenous pulse methylprednisolone. Pediatrics 2007; 119: e778e782.Google Scholar
7. Al Shibli, A, Al Attrach, I, Hamdan, MA. Bradycardia following oral corticosteroid use: case report and literature review. Arab J Nephrol Transplant 2012; 5: 4749.Google Scholar
8. Van der Gugten, A, Bierings, M, Frenkel, J. Glucocorticoid-associated bradycardia. J Pediatr Hematol Oncol 2008; 30: 172175.Google Scholar
9. Olgin, JE, Zipes, D. Specific arrhythmias: diagnosis and treatment. In Libby P,, Bonow RO, Mann DL, Zipes DP, (eds) Braunwald’s Heart Disease – A text book of Cardiovascular Medicine, 8th edn. Saunders, Philadelphia, PA, 2008: 884893.Google Scholar
10. Pappone, C, Santinelli, V. Electrophysiology testing and catheter ablation are helpful when evaluating asymptomatic patients with Wolff-Parkinson-White pattern: the pro perspective. Card Electrophysiol Clin 2015; 7: 371376.Google Scholar