Hostname: page-component-5c6d5d7d68-wbk2r Total loading time: 0 Render date: 2024-08-28T01:49:09.192Z Has data issue: false hasContentIssue false
  • English
  • Français

Successful treatment of neonatal pulmonary thrombosis in congenital nephrotic syndrome

Published online by Cambridge University Press:  25 May 2012

Krit Makonkawkeyoon ,
Suchaya Silvilairat  and
Wattana Chartapisak
Krit Makonkawkeyoon
Affiliation:
Division of Pediatric Cardiology, Department of Pediatrics, Chiang Mai University, Chiang Mai, Thailand
Suchaya Silvilairat*
Affiliation:
Division of Pediatric Cardiology, Department of Pediatrics, Chiang Mai University, Chiang Mai, Thailand
Wattana Chartapisak
Affiliation:
Division of Pediatric Nephrology, Faculty of Medicine, Department of Pediatrics, Chiang Mai University, Chiang Mai, Thailand
*
Correspondence to: Dr S. Silvilairat, MD, Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand. Tel: 66 89 761 2855; Fax: 66 53 94 6461; E-mail: ssamana@med.cmu.ac.th
Get access Rights & Permissions [Opens in a new window]

Abstract

The incidence of neonatal thrombosis has been increasing in recent times because of the use of a central venous catheter. A treatment modality consisting of fibrinolytic agents has been administered for this life-threatening condition. This case report presents the successful management of a pulmonary artery thrombosis with a recombinant tissue-type plasminogen activator in a patient with neonatal congenital nephrotic syndrome.

Keywords

Recombinant tissue-type plasminogen activatorfibrinolytic agentpulmonary arterial thrombosis
Type
Brief Report
Information
Cardiology in the Young , Volume 23 , Issue 2 , April 2013 , pp. 271 - 273
Copyright
Copyright © Cambridge University Press 2012 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Papez, KE, Smoyer, WE. Recent advances in congenital nephrotic syndrome. Curr Opin Pediatr 2004; 16: 165–170.Google Scholar
2. Hartmann, J, Hussein, A, Trowitzsch, E, Becker, J, Hennecke, KH. Treatment of neonatal thrombus formation with recombinant tissue plasminogen activator: six years experience and review of the literature. Arch Dis Child Fetal Neonatal Ed 2001; 85: F18–F22.Google Scholar
3. Ferrari, F, Vagnarelli, F, Gargano, G, et al. Early intracardiac thrombosis in preterm infants and thrombolysis with recombinant tissue type plasminogen activator. Arch Dis Child Fetal Neonatal Ed 2001; 85: F66–F69.Google Scholar
4. Alkalay, AL, Mazkereth, R, Santulli, T Jr, Pomerance, JJ. Central venous line thrombosis in premature infants: a case management and literature review. Am J Perinatol 1993; 10: 323–326.Google Scholar
5. Kändler, C, Ries, M, Rupprecht, T, Ruder, H, Harms, D. Successful systemic low-dose lysis of a caval thrombus by rt-PA in a neonate with congenital nephrotic syndrome. J Pediatr Hematol Oncol 1997; 19: 348–350.Google Scholar