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A rare case of severe Ebstein’s anomaly and hepatoblastoma in a neonate

Published online by Cambridge University Press:  22 January 2024

Julia R. Bendorf ,
Cecilia A. Albaro  and
Harma K. Turbendian Open the ORCID record for Harma K. Turbendian [Opens in a new window]
Julia R. Bendorf
Affiliation:
University of Illinois College of Medicine - Peoria, Peoria, IL, USA
Cecilia A. Albaro
Affiliation:
Division of Pediatric Cardiology, Department of Pediatrics, University of Illinois College of Medicine - Peoria, Peoria, IL, USA
Harma K. Turbendian*
Affiliation:
Pediatric and Congenital Heart Surgery, OSF Children’s Hospital of Illinois, Peoria, IL, USA Department of Surgery, University of Illinois College of Medicine - Peoria, Peoria, IL, USA
*
Corresponding author: H. K. Turbendian; Email: hkturbendian@gmail.com
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Abstract

Primary liver tumours in neonates with single-ventricle palliation are exceedingly rare. We present the first reported case of neonatal hepatoblastoma with severe Ebstein’s anomaly following Starnes procedure. The patient’s postoperative course highlights the challenges and complications in simultaneous management of these diagnoses. Transition from shunted single-ventricle physiology to bidirectional cavopulmonary connection improved end-organ function, permitting more aggressive hepatic malignancy treatment.

Keywords

univentricular heartneonatetumour (hepatic)
Type
Brief Report
Information
Cardiology in the Young , Volume 34 , Issue 4 , April 2024 , pp. 927 - 929
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Copyright
© The Author(s), 2024. Published by Cambridge University Press

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References

Cleveland, JD, Starnes, VA. Simple, reproducible, and consistent physiology: the argument for single-ventricle repair in critically ill neonates with ebstein anomaly. JTCVS Tech 2021; 10: 428–432. DOI: 10.1016/j.xjtc.2021.02.051.CrossRefGoogle ScholarPubMed
López-Terrada, DH. Hepatoblastoma. Diagn Histopathol 2014; 20: 67–75. DOI: 10.1016/j.mpdhp.2014.01.002.CrossRefGoogle Scholar
Kahla, JA, Siegel, DA, Dai, S, et al. Incidence and 5-year survival of children and adolescents with hepatoblastoma in the United States. Pediatr Blood Cancer 2022; 69: e29763 DOI: 10.1002/pbc.29763.CrossRefGoogle ScholarPubMed
Windom, MO, Campbell, MJ. Hepatoblastoma diagnosed in infancy occurring in single-ventricle patients: a case series. Cardiol Young 2020; 30: 1967–1969. DOI: 10.1017/S1047951120003042.CrossRefGoogle ScholarPubMed
Ansell, P, Mitchell, CD, Roman, E, Simpson, J, et al. Relationships between perinatal and maternal characteristics and hepatoblastoma: a report from the UKCCS. Eur J Cancer 2005; 41: 741–748. DOI: 10.1016/j.ejca.2004.10.024.CrossRefGoogle ScholarPubMed
Attenhofer Jost, CH, Connolly, HM, Dearani, JA, et al. Ebstein’s anomaly. Circulation 2007; 115: 277–285. DOI: 10.1161/CIRCULATIONAHA.106.619338.CrossRefGoogle ScholarPubMed
Starnes, VA, Pitlick, PT, Bernstein, D, et al. Ebstein’s anomaly appearing in the neonate. J Thorac Cardiovasc Surg 1991; 101: 1082–1087. DOI: 10.1016/S0022-5223(19)36627-9.CrossRefGoogle ScholarPubMed
Chen, Z, Dong, R. Advances in the conventional clinical treatment for hepatoblastoma and therapeutic innovation. World J Pediatr Surg 2021; 4: e000220. DOI: 10.1136/wjps-2020-000220.CrossRefGoogle ScholarPubMed