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Pulmonary hypertension and mitral regurgitation in an infant with an anatomically normal mitral valve

Published online by Cambridge University Press:  04 December 2020

Ryan Hoang
Affiliation:
Section of Cardiac Surgery, Department of Surgery, University of Chicago, Chicago, IL, USA
William Cohen
Affiliation:
Section of Cardiac Surgery, Department of Surgery, University of Chicago, Chicago, IL, USA
Shireen Mukadam
Affiliation:
Advocate Children’s Heart Institute, Advocate Children’s Hospital, Oak Lawn, IL, USA
Pamela Combs
Affiliation:
Section of Cardiac Surgery, Department of Surgery, University of Chicago, Chicago, IL, USA
Tarek Husayni
Affiliation:
Advocate Children’s Heart Institute, Advocate Children’s Hospital, Oak Lawn, IL, USA
Chawki El-Zein
Affiliation:
Advocate Children’s Heart Institute, Advocate Children’s Hospital, Oak Lawn, IL, USA
Luca Vricella
Affiliation:
Section of Cardiac Surgery, Department of Surgery, University of Chicago, Chicago, IL, USA Advocate Children’s Heart Institute, Advocate Children’s Hospital, Oak Lawn, IL, USA
Narutoshi Hibino*
Affiliation:
Section of Cardiac Surgery, Department of Surgery, University of Chicago, Chicago, IL, USA Advocate Children’s Heart Institute, Advocate Children’s Hospital, Oak Lawn, IL, USA
*
Author for correspondence: Narutoshi Hibino, MD/PhD, Section of Cardiac Surgery, Department of Surgery, The University of Chicago, 5841 S. Maryland, Rm E-500, MC5040, Chicago, IL 60637, USA. Tel: 773–834–3707; Fax: 773–702–4187. E-mail: nhibino@surgery.bsd.uchicago.edu

Abstract

A full-term, female presented on her date of birth with severe pulmonary hypertension (PH) and mitral regurgitation (MR), requiring veno-arterial extracorporeal membrane oxygenation. After the treatment, her PH and MR were resolved with no anatomic abnormality present. We propose a positive feedback loop of PH causing right ventricular dilation and interventricular septal shifts, worsening MR, and elevated left atrial, and potentially pulmonary, pressures.

Type
Brief Report
Copyright
© The Author(s), 2020. Published by Cambridge University Press

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References

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Pulmonary hypertension and mitral regurgitation in an infant with an anatomically normal mitral valve
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