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Psychological functioning in paediatric patients with single ventricle heart disease: a systematic review

Published online by Cambridge University Press:  20 January 2022

Amanda D. McCormick*
Affiliation:
Department of Pediatrics, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA
Megan M. Wilde
Affiliation:
Department of Pediatrics, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA
Christine E. Charpie
Affiliation:
College of Literature, Science and the Arts, University of Michigan, Ann Arbor, MI, USA
Kate M. Saylor
Affiliation:
Taubman Health Sciences Library, University of Michigan, Ann Arbor, MI, USA
Sunkyung Yu
Affiliation:
Department of Pediatrics, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA
Kurt R. Schumacher
Affiliation:
Department of Pediatrics, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA
Melissa K. Cousino
Affiliation:
Department of Pediatrics, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA
*
Author for correspondence: Amanda D. McCormick, MD, Department of Pediatrics, Michigan Medicine, University of Michigan, 1500 E Medical Center Dr., Ann Arbor, MI 48109, USA. Tel: +1 330-289-4871. E-mail: acdelong@med.umich.edu

Abstract

Background:

Patients with single ventricle heart disease are living into adulthood due to medical and surgical advancements but have significant physical comorbidities and an increased risk for psychological comorbidities compared to healthy subjects or those with other CHD diagnoses. This study aimed to systematically review psychological functioning in paediatric single ventricle heart disease.

Methods:

Literature was searched using PubMed, Embase, PsycInfo, CINAHL Complete and Scopus. Peer-reviewed articles that included patients ages 0–25 years with single ventricle heart disease, and quantitative measures of psychological outcomes were included. Meta-analysis using a fixed-effect model was conducted for internalising and externalising t-scores, utilised by the Achenbach Child Behavior Checklist.

Results:

Twenty-nine records met the criteria for inclusion. 13/24 studies demonstrated increased risk for internalising disorders, such as anxiety/depression; 16/22 studies demonstrated risk for externalising disorders, such as attention or behavioural problems. Meta-analysis of four studies revealed that paediatric single ventricle heart disease patients had no significant difference in internalising and externalising t-scores compared to normative values.

Conclusions:

The current review demonstrates the need for further studies to better understand psychological functioning in patients with single ventricle heart disease, with a majority of studies showing increased risk for psychological problems despite no difference seen in a small meta-analysis. This summary of the literature underscores the need for regular psychological screening, earlier intervention and integrated mental health therapies in paediatric single ventricle heart disease.

Type
Review
Copyright
© The Author(s), 2022. Published by Cambridge University Press

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