Hostname: page-component-7bb8b95d7b-495rp Total loading time: 0 Render date: 2024-10-05T23:04:34.297Z Has data issue: false hasContentIssue false

Mathematical modelling of the impact of preoperative hypertrophy on the outcomes of completion of the Fontan circuit

Published online by Cambridge University Press:  26 October 2005

Andrea Ripoli
Affiliation:
Clinical Physiology Institute – CNR, “G. Pasquinucci” Hospital, Massa, Italy
Sergio Berti
Affiliation:
Clinical Physiology Institute – CNR, “G. Pasquinucci” Hospital, Massa, Italy
Daniele Della Latta
Affiliation:
Clinical Physiology Institute – CNR, “G. Pasquinucci” Hospital, Massa, Italy
Emiliano Rocca
Affiliation:
Clinical Physiology Institute – CNR, “G. Pasquinucci” Hospital, Massa, Italy
Adrian Crucean
Affiliation:
Clinical Physiology Institute – CNR, “G. Pasquinucci” Hospital, Massa, Italy
Vincenzo Stefano Luisi
Affiliation:
Clinical Physiology Institute – CNR, “G. Pasquinucci” Hospital, Massa, Italy

Extract

The identification of the important relationship between shape and function of ventricular chambers represents a milestone of modern cardiology. Application of the law of Laplace for an ideal sphere furnishes intuitive insights on the progression of heart failure. A dilated heart, by virtue of its large size, must generate greater stress in the myocardial wall to achieve sufficient pressure so as to eject the required amount of blood. The mural hypertrophy represents a compensatory mechanism, guaranteeing a lower stress. When the ratio between the radius of the chamber and the thickness of its wall increases abnormally, the heart fails.

Type
Second International Workshop
Copyright
© 2005 Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)