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Tumeurs Cerebrales de l'enfant en milieu Canadien-Francais

Published online by Cambridge University Press:  18 September 2015

F. Renevey ,
Y. Amyot ,
G. Geoffroy  and
M. Vanasse
F. Renevey
Affiliation:
Service de Neurologie, Département de Pédiatric, Hôpital Sainte-Justine, Université de Montréal, Montréal, Québec, Canada
Y. Amyot
Affiliation:
Service de Neurologie, Département de Pédiatric, Hôpital Sainte-Justine, Université de Montréal, Montréal, Québec, Canada
G. Geoffroy*
Affiliation:
Service de Neurologie, Département de Pédiatric, Hôpital Sainte-Justine, Université de Montréal, Montréal, Québec, Canada
M. Vanasse
Affiliation:
Service de Neurologie, Département de Pédiatric, Hôpital Sainte-Justine, Université de Montréal, Montréal, Québec, Canada
*
Hôpital Ste-Justine, 3175 Chemin Côte Ste-Catherine, Montréal, Québec, Canada, H3T 1C5
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Summary:

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Between 1964 and 1976, we have seen 197 cases of cerebral tumors in children. We have studied the frequency of each histological group of tumors, their localization, the results of the clinical investigation, their clinical manifestations and the prognosis for each group.

This study has confirmed that in children brain tumors are more frequently localized in the posterior fossa (56.4%). As in other series, tumors derived from the glia represent nearly 80% of the total. Clinically, increased intra-cranial pressure is the most frequent manifestation of posterior fossa lesion (75% of cases) while cerebellar involvement was seen in 60% of these childdren. Brain stem lesions and supratentorial tumors are more insidious in their presentation and their clinical manifestations more diversified.

The EEG appeared useful in the investigation of brain tumors and showed irregularities in 78% of our patients. However, a more specific diagnosis required more invasive techniques such as angiography, pneumoencephalography or ventriculography.

As in previous series, the mortality rate remained high in the children we have followed, particularly for some groups of tumors (glioblastoma, medulloblastoma, brain stem lesions). It is to be hoped that with the introduction of the CT Scan, the improvement of neurosurgical techniques and the use of immuno and chemotherapy, the prognosis may be improved.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 6 , Issue 3 , August 1979 , pp. 329 - 335
Copyright
Copyright © Canadian Neurological Sciences Federation 1979

References

Ambramson, N., Raben, M., Cavanaugh, P.J. (1974). Brain tumours in children: Analysis of 136 cases. Radiology: 112: 669–672.CrossRefGoogle Scholar
Aron, B.S. (1971). Medulloblastoma in children. Twenty-two year’s experience with radiation therapy. Amer. J. Dis. Child. 121: 314–317.CrossRefGoogle Scholar
Bailey, P., Buchanan, D.N., Bucy, P.C. (1939). Intracranial tumours of infancy and childhood. Chicago: University of Chicago Press.Google Scholar
Barone, B.M., Elfidge, A.R. (1970). Ependymomas. A clinical survey. J. Neurosurg. 33: 428–438.CrossRefGoogle ScholarPubMed
Bergstrand, C.G., Bergstedt, J., Herrlin, K.M. (1958). Paediatricaspects of brain tumours in infancy and childhood. Acta. Paediatrica Scandinav. 47: 688–698.CrossRefGoogle Scholar
Dohrmann, G.J., Farwell, J.R., Flannery, B.S. (1976). Ependymomas and ependymoblastomas in children. J. Neurosurg. 45: 273–283.CrossRefGoogle ScholarPubMed
Gawler, J., Bull, J.W., Du Boulay, G.H. (1974). Computer assisted tomography (EMI-Scanner). Its place in investigation of suspected intracranial tumours. Lancet: 2: 419–423.CrossRefGoogle ScholarPubMed
Gawler, J., Du Boulay, G., Bull, J.W.B. (1976). A comparison of computer assisted tomography (EMI-Scanner) with conventionnal neuroradiologic methods in the investigation of patients suspected of intracranial tumour. J. Can. Assoc. Radiol. 27: 157–169.Google Scholar
Geissinger, J.D., Bucy, P.C. (1971). Astrocytomas of the cerebellum in children. Long-Term study. Arch. Neurol. 24: 125–135.CrossRefGoogle ScholarPubMed
Gjerris, F., Klee, J.G. and Klinken, L. (1976). Malignancy grade and long-term survival in brain tumours of infancy and childhood. Acta Neurol. Scandinav. 53: 61–71.CrossRefGoogle ScholarPubMed
Gjerris, F. (1976). Clinical aspects and long-term prognosis of intracranial tumours in infancy and childhood. Develop. Med. Child Neurol. 18: 145–159.CrossRefGoogle Scholar
Gjerris, F. (1978). Clinical aspect and long-term prognosis of infratentorial intracranial tumours in infancy and childhood. Act. Neurol. Scandinav. 57: 31–52.CrossRefGoogle ScholarPubMed
Gol, A., Mckissock, W. (1959). The cerebellar astrocytomas. A report on 98 verified cases. J. Neurosurg. 16: 287–296.CrossRefGoogle ScholarPubMed
Hoff, J.T. and Patterson, R.H. (1972). Craniopharyngiomas in children and adults. J. Neurosurgery 36: 299–302.CrossRefGoogle ScholarPubMed
Katz, E.L. (1975). Late results of radical excision of craniopharyngiomas in children. J. Neurosurg. 42: 86–93.CrossRefGoogle ScholarPubMed
Keith, H.M., Craig, W.M., Kernohan, J.W. (1949). Brain tumours in children. Pediatrics. 3: 839–844.CrossRefGoogle ScholarPubMed
Kernohan, J.W., Mabon, R.F., Svien, H.J., Adson, A.W. (1949).A simplified classification of gliomas. Proc. Staff Meetings Mayo Clinic. 24: 71–75.Google Scholar
Lee, F. (1975). Radiation of infratentorial and supratentorial brainstem tumours. J. Neurosurg. 43: 65–68.CrossRefGoogle Scholar
McFarland, D.R., Horwitz, H., Saenger, EL (1969). Medulloblastoma: A review of prognosis and survival. Br. J. Radiol. 42: 198–214.CrossRefGoogle ScholarPubMed
Marsden, H.B., Stewart, J.K. (1968). Tumours in children. Berlin. Springer ed.CrossRefGoogle ScholarPubMed
Matson, D.D. (1956). Cerebellar astrocytoma in childhood. J. Pediatr. 18: 150–158.CrossRefGoogle ScholarPubMed
Matson, D.D. (1969). Neurosurgery of infancy and childhood 2nd Edition, p. 410–479. Charles C. Thomas Publisher — Springfield.Google Scholar
Mealey, J. JR. , Hall, P.V. (1977). Medulloblastoma in children. Survival and treatment. J. Neurosurg. 46: 56–64.CrossRefGoogle ScholarPubMed
New, P.J.F., Scott, W.R., Schnur, J.A. (1975). Computed tomography with the EMI-Scanner in the diagnosis of primary and metastatic neoplasms. Radiology 114: 75–87.CrossRefGoogle Scholar
Ommaya, A.K. (1976).Immunotherapy of gliomas: A review. In Advances in Neurology. Vol. 15 pp. 337–349, Raven Press.Google ScholarPubMed
Onoyama, Y., Abe, M., Takahashi, M., Yabumoto, E., Sakamoto, T., Sakamoto, T. (1975). Radiation therapy of brain tumors in children. Radiology 115: 687–693.CrossRefGoogle ScholarPubMed
Pons, A., Armand, J.P., Combes, P.F., Nadal, P. (1975). Survie des malades atteints de tumeurs cérébrales sustentorielles primitives en fonction des associations thérapeutiques. Neurochirurgie: 21: 408–410.Google Scholar
Quest, D.O., Brisman, R., Antunes, J.L., Housepian, E.M. (1978). Periodof risk for recurrence in medulloblastoma. J. Neurosurg. 48: 159–163.CrossRefGoogle Scholar
Rubinstein, L.J. (1972). Tumors of the central nervous system. In Atlas of Tumor Pathology, fasc. 6 Published by the Armed Forces Institute of Pathology.Google Scholar
Schoenberg, B.S., Schoenberg, D.C., Christine, B.W., Gomez, R.R. (1975). The epidemiology of primary intracranial neoplasms of childhood: A population study. Neurology. 25: 256.Google Scholar
Smith, W.A., Fincher, E.F. (1942). Intracranial tumors in children: Preliminary study of 100 cases. South Med. J. 35: 547–554.CrossRefGoogle Scholar
Svolos, D.G. (1969). Craniopharyngiomas: A study based on 108 verified cases.Google ScholarPubMed
Villanti, R., Gaini, S.M., Tomei, G. (1975). Follow-up study of brainstem tumors in children. Child’s Brain 1: 126–135.Google Scholar
Walker, M.D., Weiss, H.D. (1975). Chemotherapy in the treatment of malignant brain tumors. In Advances in Neurology. Vol. 13, pp. 149–191. Friedlander, W.J. edit. Raven Press.Google Scholar
Young, J-L. Jr., Miller, R.W. (1975). Incidence of malignant tumors in U.S. children. J. Pediat. 86: 254–258.CrossRefGoogle ScholarPubMed