Hostname: page-component-77c89778f8-n9wrp Total loading time: 0 Render date: 2024-07-21T07:10:02.086Z Has data issue: false hasContentIssue false

Paraneoplastic Subacute Necrotic Myelopathy

Published online by Cambridge University Press:  18 September 2015

Adrian Handforth
Affiliation:
Departments of Medicine and Pathology, Queen’s University and Kingston General Hospital, Kingston, Ontario
Sukriti Nag*
Affiliation:
Departments of Medicine and Pathology, Queen’s University and Kingston General Hospital, Kingston, Ontario
Daniel Sharp
Affiliation:
Departments of Medicine and Pathology, Queen’s University and Kingston General Hospital, Kingston, Ontario
David M. Robertson
Affiliation:
Departments of Medicine and Pathology, Queen’s University and Kingston General Hospital, Kingston, Ontario
*
Department of Pathology, Queen’s University, Kingston, Ontario, Canada, K7L 3N6.
Rights & Permissions [Opens in a new window]

Summary:

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

A 79 year old male acutely developed a Brown-Sequard syndrome two weeks following resection of renal cell carcinoma. The subsequent clinical course was marked by subacute progression of spinal cord signs. Pathologic studies showed extensive multifocal spinal cord necrosis that could not be attributed to vascular occlusion or to vasculitis. This case appears to be a rare example of paraneoplastic subacute necrotic myelopathy.

Type
Original Articles
Copyright
Copyright © Canadian Neurological Sciences Federation 1983

References

Case records of the Massachusetts General Hospital—Case 26. (1976). N. Engl. J. Med. 294: 11471454.CrossRefGoogle Scholar
Grisold, W., Lutz, D., Wolf, D. (1980). Necrotizing myelopathy associated with acute lymphoblastic leukemia. Acta Neuropathol. (Berl.) 49: 231235.CrossRefGoogle ScholarPubMed
Folliss, A.G.H., Netsky, M.G.Progressive necrotic myelopathy, in: Handbook of Clinical Neurology, vol. 9, Ed. Vinken, P.J., Bruyn, G.W., North Holland Publication Co., Amsterdam, 1970.Google Scholar
Lester, E.P., Feld, E., Kinzie, J.J., Wollman, R. (1979). Necrotizing myelopathy complicating Hodgkin’s disease. Arch Neurol. 36:583585.CrossRefGoogle ScholarPubMed
Mancall, E.L., Rosales, R.K. (1964). Necrotizing myelopathy associated with visceral carcinoma. Brain 87: 639656.CrossRefGoogle ScholarPubMed
Nishida, T., Ziegler, D.K. (1973). Acute necrotic myelopathy in association with lymphoma cells of the reticuloendothelial system, acute torticollis, and recurrent cardiac arrest. Confín. Neurol. 35: 346355.Google Scholar
Richter, R.B., Moore, R.Y. (1968). Non-invasive central nervous sytem disease associated with lymphoid tumours. Johns Hopkins Med. J. 122: 271283.Google Scholar
Sieben, G.M., De Reuck, J.L., De Bruyne, J.C., Vander Eecken, H.M. (1981). Subacute necrotic myelopathy. Its appearance eight years after cure of a breast carcinoma. Arch. Neurol. 38: 775777.CrossRefGoogle ScholarPubMed