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Nitrazepam for Periodic Movements in Sleep (Sleep-related Myoclonus)

Published online by Cambridge University Press:  18 September 2015

Harvey Moldofsky ,
Carole Tullis ,
Grace Quance  and
Franklin A. Lue
Harvey Moldofsky*
Affiliation:
Sleep Disorders Clinic, Department of Psychiatry, Toronto Western Hospital, Toronto
Carole Tullis
Affiliation:
Sleep Disorders Clinic, Department of Psychiatry, Toronto Western Hospital, Toronto
Grace Quance
Affiliation:
Sleep Disorders Clinic, Department of Psychiatry, Toronto Western Hospital, Toronto
Franklin A. Lue
Affiliation:
Sleep Disorders Clinic, Department of Psychiatry, Toronto Western Hospital, Toronto
*
Department of Psychiatry, Toronto Western Hospital, 399 Bathurst Street, Toronto, Ontario, Canada M5T 2S8
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Abstract:

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In a follow-up study (mean, approximately six months), nitrazepam was helpful in suppressing periodic movements in sleep (sleep-related myoclonus) and improving disturbed sleep physiology and daytime symptoms of 13 patients (mean age - 53 yr).

Type
Original Articles
Information
Canadian Journal of Neurological Sciences , Volume 13 , Issue 1 , February 1986 , pp. 52 - 54
Copyright
Copyright © Canadian Neurological Sciences Federation 1986

References

REFERENCES

1.Diagnostic Classification of sleep and arousal disorders: Association of Sleep Disorders Centres and the Association for the Psycho-physiological Study of Sleep, 1st ed. Sleep 1979; 2.Google Scholar
2.Coleman, RM, Bliwise, DL, Sajben, Net al. Epidemiology of periodic movements during sleep. In: Guilleminault, C and Lugaresi, E, eds. Sleep-Wake Disorders: Natural History, Epidemiology, and Long Term Evolution. New York: Raven Press, 1983, pp 217–229.Google Scholar
3.Read, DJ, Feest, TG, Nassim, MA. Clonazepam: effective treatment for restless legs syndrome in uremia. Br Med J (Clin Res) 1981; 3: 283: 855–856.CrossRefGoogle Scholar
4.Moldofsky, H, Tullis, MA, Lue, FAet al. Sleep-related myoclonus in rheumatic pain modulation disorder (Fibrositis Syndrome) and in excessive daytime somnolence. Psychosom Med 1984; 46: 145–151.CrossRefGoogle ScholarPubMed
5.Mosko, SS, Shampain, DS, Sassin, JF. Nocturnal REM latency and sleep disturbance in narcolepsy. Sleep 1984; 7: 115–125.CrossRefGoogle ScholarPubMed
6.Botez, MI. Cadotte, M, Beaulieu, et al. Neurological disorders responsive to folic acid therapy. Can Med Assoc J 1976; 115: 217–223.Google ScholarPubMed
7.Norlander, NB. Therapy in restless legs. Acta Med Scand 1953; 145: 453–457.Google Scholar
8.Ware, JC, Pittard, JT, Blumoff, RL. Treatment of sleep-related myoclonus with an alpha-receptor blocker. Sleep Res 1981; 10: 242.Google Scholar
9.Bellinghier, G, Savica, V, Mallamace, Aet al. Restless legs syndrome and therapeutic effect of lorazepam: preliminary report. (Abstract) Proc Eur Dial Transplant Assoc 1983; 10 (20th Congress).Google Scholar
10.Mitler, M, Browman, CP, Gujavarty, K, Timms, RM, Menn, SJ. Nocturnal myoclonus treatment efficiency of clonazepam and temazepam. (Abstract) Sleep Res 1980; 9: 58.Google Scholar
11.Kangas, L, Breimer, DD. Clinical pharmacokinetics of nitrazepam. Clin Pharmacokinet 1981; 6: 346–366.CrossRefGoogle ScholarPubMed
12. Bellantuona, C, Reggi, V, Tognoni, G, Garattini, S. Benzodiazepines: Clinical pharmacology and therapeutic use. Drugs 1980; 19: 195–219.CrossRefGoogle Scholar
13.Rechtschaffen, A, Kales, A, eds. A manual of standardized terminology, techniques, and scoring system for sleep stages of human subjects. Washington: NIH Pub No 204, 1968.Google Scholar
14.Moldofsky, H, Scarisbrick, P, England, R, Smythe, H. Musculoskeletal symptoms and nonREM sleep disturbance in patients with “Fibrositis Syndrome” and healthy subjects. Psychosom Med 1975; 37: 341–351.CrossRefGoogle Scholar
15.Hoddes, E, Dement, WC, Zarcone, V. The development and use of the Stanford Sleepiness Scale (SSS). Psychophysiology 1972; 9: 150.Google Scholar
16.Greenblatt, DJ, Allen, MD. Toxicity of nitrazepam in the elderly: a report from the Boston Collaborative Drug Surveillance Program. Br J Clin Pharmacol 1978; 5: 407–413.CrossRefGoogle ScholarPubMed
17.Mattila, MJ, Aranko, K, Matilla, ME, Stromberg, C. Objective and subjective assessment of hangover during subacute administration of temazepam and nitrazepam to healthy subjects. Eur J Clin Pharmacol 1984: 26: 375–380.CrossRefGoogle ScholarPubMed
18.Coleman, RM, Pollak, CP, Weitzman, ED. Periodic movements in sleep (Nocturnal Myoclonus): Relation to sleep disorders. Ann Neurol 1980; 8: 416–421.CrossRefGoogle ScholarPubMed
19.Martin, TL, Brown, CL, Doble, A. Multiple benzodiazepine receptors: Structures in the brain or structures in the mind? A critical review. Life Sci 1983; 32: 1925–1933.CrossRefGoogle ScholarPubMed