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Neural Transplantation in Spinal Cord Injury

Published online by Cambridge University Press:  02 March 2017

S.D. Christie  and
I. Mendez
S.D. Christie
Affiliation:
Neural Transplantation Laboratory, Department of Anatomy and Neurobiology and Department of Surgery (Division of Neurosurgery), Dalhousie University, Halifax, Nova Scotia, Canada
I. Mendez*
Affiliation:
Neural Transplantation Laboratory, Department of Anatomy and Neurobiology and Department of Surgery (Division of Neurosurgery), Dalhousie University, Halifax, Nova Scotia, Canada
*
Neural Transplantation Laboratory, Room 12D, Sir Charles Tupper Medical Building, Dalhousie University, Halifax, Nova Scotia, Canada B3H 4H7
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Abstract:

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Although medical advancements have significantly increased the survival of spinal cord injury patients, restoration of function has not yet been achieved. Neural transplantation has been studied over the past decade in animal models as a repair strategy for spinal cord injury. Although spinal cord neural transplantation has yet to reach the point of clinical application and much work remains to be done, reconstructive strategies offer the greatest hope for the treatment of spinal cord injury in the future. This article presents the scientific basis of neural transplantation as a repair strategy and reviews the current status of neural transplantation in spinal cord injury.

Résumé:

RÉSUMÉ:

Bien que les progrès de la médecine aient augmenté significativement la survie des patients ayant subi un traumatisme de la moelle épinière, la restauration de la fonction n'a pas encore été réalisée. La transplantation neurale a été étudiée pendant la dernière décennie chez des modèles animaux comme stratégie de réparation de la lésion de la moelle. Même si la transplantation neurale n'a pas atteint le stade de l'application clinique et qu'il reste beaucoup de travail à faire, ce sont les stratégies de reconstruction qui offrent le plus d'espoir dans le traitement des traumatismes de la moelle épinière. Cet article présente les bases scientifiques de la transplantation neurale comme stratégie de réparation et revoit l'état actuel de la transplantation dans les traumatismes de la moelle épinière.

Type
Review Article
Information
Canadian Journal of Neurological Sciences , Volume 28 , Issue 1 , February 2001 , pp. 6 - 15
Copyright
Copyright © The Canadian Journal of Neurological 2001

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