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Immunofluorescent Staining of Rat Brain Glial Cells With Multiple Sclerosis Serum
Published online by Cambridge University Press: 18 September 2015
Summary:
Antibodies directed against glial cells may be involved in autoimmunity in multiple sclerosis (MS). Using a tissue culture system, the presence of glial cell antibodies in MS-patient serum was detected through immunofluorescent technique. Thirty one of 73 MS-sera were strongly positive for anti-glial cells, 13 were equivocal and 29 were negative. The antibody staining was either cytoplasmic or associated with cell surface membrane, and involved IgG type of antibody.
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- Copyright © Canadian Neurological Sciences Federation 1981
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