Hostname: page-component-788cddb947-jbkpb Total loading time: 0 Render date: 2024-10-13T23:51:18.544Z Has data issue: false hasContentIssue false

Deprenyl: The Exciting Possibility of Protective Effect

Published online by Cambridge University Press:  18 September 2015

J. David Grimes*
Affiliation:
Division of Neurology and Loeb Medical Research Institute, Ottawa Civic Hospital, University of Ottawa, Ottawa
*
Division of Neurology and Loeb Medical Research Institute, Ottawa Civic Hospital, University of Ottawa, 1053 Carling Avenue, Ottawa, Ontario, Canada KIY 4E9
Rights & Permissions [Opens in a new window]

Abstract

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Focus on Parkinson's Disease
Copyright
Copyright © Canadian Neurological Sciences Federation 1991

References

1.Parkinson Study Group. Datatop: A multicenter controlled clinical trial in early Parkinson’s disease. Arch Neurol 1989; 46: 10521060.CrossRefGoogle Scholar
2.Grimes, JD, Hassan, MN, Thakar, J.Antioxidant therapy in Parkinson’s disease. Can J Neurol Sci 1987; 14: 483487.CrossRefGoogle ScholarPubMed
3.Parkinson Study Group. Effect of deprenyl on the progression of disability in early Parkinson’s disease. N Engl J Med 1989; 321: 13641371.CrossRefGoogle Scholar
4.Landau, WM. Pyramid sale in the bucket shop: Datatop bottoms out. Neurology 1990; 40: 13371339.CrossRefGoogle ScholarPubMed
5.Csanda, E, Tarczy, M.Selegiline in the early late phases of Parkinson’s disease. J Neural Transm 1987; 25: 105113.Google ScholarPubMed
6.Elizan, TS, Yahr, MD, Moros, DA, et al. Selegiline use to prevent progression of Parkinson’s disease. Arch Neurol 1989; 46: 12751279.CrossRefGoogle ScholarPubMed
7.Myllyla, VV, Sotaniemi, KA, Tuominen, J, et al. Selegiline as primary treatment in early phase Parkinson’s disease – an interim report. Acta Neurol Scand 1989; 126: 177182.CrossRefGoogle ScholarPubMed
8.Teravainen, H.Selegiline in Parkinson’s disease. Acta Neurol Scand 1990; 81: 333336.CrossRefGoogle ScholarPubMed
9.Tetrad, JW, Langston, JW.The effect of deprenyl (selegiline) on the natural history of Parkinson’s disease. Science 1989; 245: 519522.CrossRefGoogle Scholar
10.Knoll, J.Deprenyl (selegiline): the history of the its development and pharmacological action. Acta Neurol Scand 1983; 95: 5780.CrossRefGoogle ScholarPubMed
11.Diamond, SG, Markham, CH, Treciokas, LJ.Double-blind trial of pergolide in Parkinson’s disease. Neurology 1985; 35: 291295.CrossRefGoogle Scholar
12.Quinn, NP.Anti-parkinsonian drugs today. Drugs 1984; 28: 236262.CrossRefGoogle ScholarPubMed
13.Stern, GM, Lees, AJ, Hardie, RJ, et al. Clinical and pharmacological problems of deprenyl (selegiline) treatment in Parkinson’s disease. Acta Neurol Scand 1983; 95: 113116.CrossRefGoogle ScholarPubMed
14.Mann, JJ, Fox-Aarons, S, Wilner, PJ, et al. A controlled study of anti-depressant efficacy and side effects of (–) –Deprenyl. Arch Gen Psychiatry 1989; 46: 4550.CrossRefGoogle Scholar