Skip to main content Accessibility help
×
Home
Hostname: page-component-99c86f546-45s75 Total loading time: 0.309 Render date: 2021-12-03T02:52:57.698Z Has data issue: true Feature Flags: { "shouldUseShareProductTool": true, "shouldUseHypothesis": true, "isUnsiloEnabled": true, "metricsAbstractViews": false, "figures": true, "newCiteModal": false, "newCitedByModal": true, "newEcommerce": true, "newUsageEvents": true }

Responses and Dialogue: Response to “Germ-Line Therapy to Cure Mitochondrial Disease: Protocol and Ethics of In Vitro Ovum Nuclear Transplantation” by Donald S. Rubenstein, David C. Thomasma, Eric A. Schon, and Michael J. Zinaman (CQ Vol 4, No 3.)

Published online by Cambridge University Press:  29 July 2009

Matthew D. Bacchetta
Affiliation:
A member of the class of 1998, Cornell University Medical College, New York.
Gerd Richter
Affiliation:
A fellow in the Center for Biomedical Ethics, University of Virginia, Department of Internal Medicine, Philipps University, Marburg, Germany.

Abstract

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Departments and Columns
Copyright
Copyright © Cambridge University Press 1996

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Rubenstein, DS, Thomasma, DC, Schon, EA, Zinaman, MJ. Germ-line therapy to cure mitochondrial disease: protocol and ethics of in vitro ovum nuclear transplantation. Cambridge Quarterly of Healthcare Ethics 1995;4:316–39.CrossRefGoogle ScholarPubMed

2. Anderson, S, Bankier, AT, Barrell, BG et al. , Sequence and organization of the human mitochondrial genome. Nature 1981;290:457–65.CrossRefGoogle ScholarPubMed

3. Wallace, DC. Report on the committee on human mitochondrial DNA. Cytogenetics and Cell Genetics 1989;51:612–21.CrossRefGoogle Scholar

4. Wallace, DC. Diseases of mitochondrial DNA. Annual Review of Biochemistry 1992;61:1174–212.CrossRefGoogle ScholarPubMed

5. Wallace, DC. Mitochondrial DNA variation in human evolution, degenerative disease, and aging. American Journal of Human Genetics 1995;57:201–23.Google ScholarPubMed

6. Wallace, DC. Mitochondrial genetics: a paradigm for aging and degenerative diseases? Science 1992;256:628–38.CrossRefGoogle ScholarPubMed

7. Walters, L. Ethical issues in human gene therapy. Journal of Clinical Ethics 1991;2:267–74.Google ScholarPubMed

8. Edwards, RG. Preconception and Preimplantation Diagnosis in Human Genetic Diseases. New York: Cambridge University Press, 1993.Google Scholar

9. Vega, MA. Gene targeting in human gene therapy. In: Vega, MA, Ed. Gene Targeting. Boca Raton, Florida: CRC Press, 1995:211–30.Google Scholar

10. Seibel, P, Trappe, J, Villani, G, Klopstock, T, Papa, S, Reichmann, H. Transfection of mitochondria: strategy towards a gene therapy of mitochondrial DNA diseases. Nucleic Acids Research 1995;23:10–7.CrossRefGoogle ScholarPubMed

6
Cited by

Send article to Kindle

To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Responses and Dialogue: Response to “Germ-Line Therapy to Cure Mitochondrial Disease: Protocol and Ethics of In Vitro Ovum Nuclear Transplantation” by Donald S. Rubenstein, David C. Thomasma, Eric A. Schon, and Michael J. Zinaman (CQ Vol 4, No 3.)
Available formats
×

Send article to Dropbox

To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

Responses and Dialogue: Response to “Germ-Line Therapy to Cure Mitochondrial Disease: Protocol and Ethics of In Vitro Ovum Nuclear Transplantation” by Donald S. Rubenstein, David C. Thomasma, Eric A. Schon, and Michael J. Zinaman (CQ Vol 4, No 3.)
Available formats
×

Send article to Google Drive

To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

Responses and Dialogue: Response to “Germ-Line Therapy to Cure Mitochondrial Disease: Protocol and Ethics of In Vitro Ovum Nuclear Transplantation” by Donald S. Rubenstein, David C. Thomasma, Eric A. Schon, and Michael J. Zinaman (CQ Vol 4, No 3.)
Available formats
×
×

Reply to: Submit a response

Please enter your response.

Your details

Please enter a valid email address.

Conflicting interests

Do you have any conflicting interests? *