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Variation in Y chromosome meiotic drive in Aedes aegypti (Diptera: Culicidae): a potential genetic approach to mosquito control

Published online by Cambridge University Press:  10 July 2009

K. O. Owusu-Daaku ,
R. J. Wood  and
R. D. Butler
K. O. Owusu-Daaku
Affiliation:
School of Biological Sciences, University of Manchester, Stopford Building, Oxford Road, Manchester, M13 9PT
R. J. Wood*
Affiliation:
School of Biological Sciences, University of Manchester, Stopford Building, Oxford Road, Manchester, M13 9PT
R. D. Butler
Affiliation:
School of Biological Sciences, University of Manchester, Stopford Building, Oxford Road, Manchester, M13 9PT
*
† Author for correspondence.
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Abstract

Reciprocal crosses between strains of Aedes aegypti (Linnaeus) from different geographical areas have revealed an unexpectedly complex pattern of holandrically inherited male biased sex ratios in F2. The variation has been interpreted in terms of a web of X–Y interactions in Fl, in which the Y chromosome may or may not show meiotic drive against the X chromosome with which it is paired. The pattern of inheritance is not in agreement with a single form of Y chromosome, driving with different degrees of intensity against Xs of different sensitivity, but indicates different forms of driving Y chromosome. A rule has emerged that if Fl males from any cross give rise to a male distorted sex ratio in their progeny (F2), the males from the reciprocal cross give rise to a normal sex ratio. All eleven newly colonized strains from Ghana showed Y meiotic drive against the Xs of five strains, one of American and four of Australian origin, although one of the eleven showed a greater degree of drive than the other ten against the same sensitive strains. The variation observed is discussed in relation to previous studies on meiotic drive by the MD haplotype, and to the possible exploitation of sex ratio distortion in controlling this potentially dangerous insect.

Type
Original Articles
Information
Bulletin of Entomological Research , Volume 87 , Issue 6 , December 1997 , pp. 617 - 623
Copyright
Copyright © Cambridge University Press 1997

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