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The double-mutation（M918I + L1014F）kdr allele is fixed in Cimex hemipterus populations in Guangxi, China

Published online by Cambridge University Press:  10 February 2020

Yuhan Zhao ,
Xiangyang Feng ,
Mei Li  and
Xinghui Qiu Open the ORCID record for Xinghui Qiu [Opens in a new window]
Yuhan Zhao
Affiliation:
State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing100101, China
Xiangyang Feng
Affiliation:
Guangxi Zhuang Autonomous Region Centre for Diseases Control and Prevention, Nanning530028, China
Mei Li
Affiliation:
State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing100101, China
Xinghui Qiu*
Affiliation:
State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing100101, China
*
Author for correspondence: Xinghui Qiu, Email: qiuxh@ioz.ac.cn
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Abstract

Four putative knockdown resistance (kdr) mutations have been documented in the voltage-gated sodium channel (VGSC) gene of Cimex hemipterus from several countries. However, no information regarding kdr mutations in any Chinese tropical bed bug population is available to date. In this study, a double-mutation（M918I + L1014F）kdr allele was identified in six C. hemipterus populations across Guangxi Zhuang Autonomous Region of China. The frequency of this allele was 100% in all the six examined populations. In addition, only two cytochrome c oxidase I (COI) gene haplotypes, with one synonymous nucleotide variation, were identified in a total of 48 individuals from six locations. The fixation and broad geographic distribution of this resistant allele questions the continued use of pyrethroids in the treatment of tropical bed bug infestations. The very low genetic diversity within and among these populations indicates that these bed bugs may have a single origin.

Keywords

Guangxi Zhuang Autonomous Region of Chinaknockdown resistancepyrethroidsTropical bed bugs
Type
Research Paper
Information
Bulletin of Entomological Research , Volume 110 , Issue 4 , August 2020 , pp. 506 - 511
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Copyright
Copyright © The Author(s), 2020. Published by Cambridge University Press

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