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Vitamin A reserve of liver in health and coronary heart disease among ethnic groups in Singapore

Published online by Cambridge University Press:  09 March 2007

N. Saha ,
T. B. Ng ,
P. Y. Tan  and
K. P. Wee
N. Saha
Affiliation:
Department of Physiology, Faculty of Medicine, National University of Singapore, 10 Kent Ridge Crescent, Singapore0511
T. B. Ng
Affiliation:
Department of Physiology, Faculty of Medicine, National University of Singapore, 10 Kent Ridge Crescent, Singapore0511
P. Y. Tan
Affiliation:
Department of Physiology, Faculty of Medicine, National University of Singapore, 10 Kent Ridge Crescent, Singapore0511
K. P. Wee
Affiliation:
Department of Pathology, Singapore General Hospital, Singapore
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Abstract

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1. The vitamin A content of human liver tissue was determined in 363 autopsy samples. The sample comprised a total of 181 subjects dying after accidents and 182 dying from coronary heart disease among Singapore ethnic groups of both sexes.

2. The medium vitamin A reserve was 146 mg/kg in accident victims and 141 mg/kg in those who had died of coronary heart disease. Of all the samples 16% contained less than 40 mg/kg, 45% had 100–300 mg/kg, while 9% contained more than 500 mg/kg liver.

3. Among the accident victims, Indians had the lowest median liver vitamin A reserve (118 mg/kg) compared with that in other ethnic groups (137 mg/kg in Chinese, 191 mg/kg in Malays, 155 mg/kg in Caucasians).

4. The ethnic distribution of vitamin A reserve in coronary deaths was similar to that in accident victims.

5. There was no significant difference between the sexes in hepatic vitamin A reserve.

6. The distribution of vitamin A reserve in all the groups was skewed to the right.

Type
Clinical and Human Nutrition papers: Studies in Man
Information
British Journal of Nutrition , Volume 60 , Issue 3 , November 1988 , pp. 407 - 412
Copyright
Copyright © The Nutrition Society 1988

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