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Influence of low dietary lipid content on anorexia and [14C]glucose uptake in the intestine of zinc-deficient mice

Published online by Cambridge University Press:  09 March 2007

S. K. Taneja  and
P. Arya
S. K. Taneja
Affiliation:
Department of Zoology, Panjab University, Chandigarh 160014, India
P. Arya
Affiliation:
Department of Zoology, Panjab University, Chandigarh 160014, India
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Abstract

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Zinc deficiency was induced in adult male mice by feeding them for 8 weeks on a purified semi-synthetic Zn-deficient diet (ZD) containing 90 g lipid/kg (60 g maize oil plus 30 g cod-liver oil). One group was then fed on a low-lipid Zn-deficient diet (ZDLR) containing 30 g cod-liver oil/kg as the sole lipid source for a further 8 weeks. At the end of the experiment the stomach clearance rate, daily food intake, body-weight gain and [14C]glucose uptake in the intestine were significantly higher in group ZDLR than in mice that continued eating the Zn-deficient lipid-adequate diet ZD, and were comparable to results for a group given a Zn-supplemented diet. These results suggest that the pathogenesis of anorexia, nutrient malabsorption and growth retardation are secondary to lipid malabsorption resulting from Zn deficiency

Keywords

Dietary lipidAnorexiaGlucose uptakeZinc deficiencyMice
Type
Metabolic Effects of Altered Zinc Status
Information
British Journal of Nutrition , Volume 68 , Issue 2 , September 1992 , pp. 505 - 514
Copyright
Copyright © The Nutrition Society 1992

References

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