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Jabuticaba juice improves postprandial glucagon-like peptide-1 and antioxidant status in healthy adults: a randomised crossover trial

Published online by Cambridge University Press:  15 November 2021

Marina Vilar Geraldi*
School of Food Engineering, University of Campinas, Campinas, SP13083-862, Brazil
Cínthia Bau Betim Cazarin
School of Food Engineering, University of Campinas, Campinas, SP13083-862, Brazil
Marcelo Cristianini
School of Food Engineering, University of Campinas, Campinas, SP13083-862, Brazil
Ana Carolina Junqueira Vasques
Laboratory of Investigation on Metabolism and Diabetes, Gastrocentro, University of Campinas, Campinas, SP, Brazil
Bruno Geloneze
Laboratory of Investigation on Metabolism and Diabetes, Gastrocentro, University of Campinas, Campinas, SP, Brazil
Mário Roberto Maróstica Júnior
School of Food Engineering, University of Campinas, Campinas, SP13083-862, Brazil
*Corresponding author: Dr Marina Vilar Geraldi, email


Jabuticaba is a Brazilian berry rich in polyphenols, which may exert beneficial effects on metabolic diseases. This randomised crossover study aimed to determine the effects of jabuticaba juice (250 ml in a portion) on postprandial response. Sixteen healthy subjects (eleven women; five men; 28·4 (sd 3·8) years old; BMI 21·7 (sd 2·3) kg/m−2) consumed two test products after fasting overnight in a randomised controlled crossover design. Each test product portion had a similar composition of sugar components: 250 ml water with glucose, fructose, coloured with artificial non-energetic food colourings (placebo), and 250 ml of jabuticaba juice. Beverages were administered immediately before a carbohydrate meal. Blood samples were collected at 0, 15, 30, 45, 60, 90 and 120 min after each test product to analyse the concentrations of glucose, insulin, C-peptide, antioxidant capacity, plasma glucagon-like peptide-1 (GLP-1) and appetite sensations. Compared with the placebo, the intake of jabuticaba juice resulted in a higher GLP-1 response as the AUC and peaking at 60 min. Jabuticaba juice also resulted in higher antioxidant capacity. Postprandial glucose, insulin, C-peptide levels and appetite sensations were not significantly different between tests. In conclusion, 250 ml of jabuticaba juice before a carbohydrate meal was able to improve the antioxidant status and GLP-1 concentrations in healthy subjects.

Research Article
© The Author(s), 2021. Published by Cambridge University Press on behalf of The Nutrition Society

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Jabuticaba juice improves postprandial glucagon-like peptide-1 and antioxidant status in healthy adults: a randomised crossover trial
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