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Effects of folic acid and cobalt sulphate supplementation on growth performance, nutrient digestion, rumen fermentation and blood metabolites in Holstein calves

Published online by Cambridge University Press:  21 June 2021

Yongjia Liu ,
Jing Zhang ,
Cong Wang ,
Qiang Liu Open the ORCID record for Qiang Liu[Opens in a new window] ,
Gang Guo ,
Wenjie Huo ,
Lei Chen ,
Yanli Zhang ,
Caixia Pei  and
Shuanlin Zhang
Yongjia Liu
Affiliation:
College of Animal Science, Shanxi Agricultural University, Taigu030801, Shanxi Province, People’s Republic of China
Jing Zhang
Affiliation:
College of Animal Science, Shanxi Agricultural University, Taigu030801, Shanxi Province, People’s Republic of China
Cong Wang
Affiliation:
College of Animal Science, Shanxi Agricultural University, Taigu030801, Shanxi Province, People’s Republic of China
Qiang Liu*
Affiliation:
College of Animal Science, Shanxi Agricultural University, Taigu030801, Shanxi Province, People’s Republic of China
Gang Guo
Affiliation:
College of Animal Science, Shanxi Agricultural University, Taigu030801, Shanxi Province, People’s Republic of China
Wenjie Huo
Affiliation:
College of Animal Science, Shanxi Agricultural University, Taigu030801, Shanxi Province, People’s Republic of China
Lei Chen
Affiliation:
College of Animal Science, Shanxi Agricultural University, Taigu030801, Shanxi Province, People’s Republic of China
Yanli Zhang
Affiliation:
College of Animal Science, Shanxi Agricultural University, Taigu030801, Shanxi Province, People’s Republic of China
Caixia Pei
Affiliation:
College of Animal Science, Shanxi Agricultural University, Taigu030801, Shanxi Province, People’s Republic of China
Shuanlin Zhang
Affiliation:
College of Animal Science, Shanxi Agricultural University, Taigu030801, Shanxi Province, People’s Republic of China
*
*Corresponding author: Qiang Liu, email liuqiangabc@163.com
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Abstract

To investigate the influences of cobalt (Co) and folic acid (FA) on growth performance and rumen fermentation, Holstein male calves (n 40) were randomly assigned to four groups according to their body weights. Cobalt sulphate at 0 or 0·11 mg Co/kg DM and FA at 0 or 7·2 mg/kg DM were used in a 2 × 2 factorial design. Average daily gain was elevated with FA or Co supplementation, but the elevation was greater for supplementing Co in diets without FA than with FA. Supplementing FA or Co increased DM intake and total-tract nutrient digestibility. Rumen pH was unaltered with FA but reduced with Co supplementation. Concentration of rumen total volatile fatty acids was elevated with FA or Co inclusion. Acetate percentage and acetate to propionate ratio were elevated with FA inclusion. Supplementing Co decreased acetate percentage and increased propionate percentage. Activities of xylanase and α-amylase and populations of total bacteria, fungi, protozoa, Ruminococcus albus, Fibrobacter succinogenes and Prevotella ruminicola increased with FA or Co inclusion. Activities of carboxymethyl-cellulase and pectinase increased with FA inclusion and population of methanogens decreased with Co addition. Blood folates increased and homocysteine decreased with FA inclusion. Blood glucose and vitamin B12 increased with Co addition. The data suggested that supplementing 0·11 mg Co/kg DM in diets containing 0·09 mg Co/kg DM increased growth performance and nutrient digestibility but had no improvement on the effects of FA addition in calves.

Keywords

Cobalt sulphateFolic acidGrowth performanceRumen fermentationCalves
Type
Research Article
Information
British Journal of Nutrition , Volume 127 , Issue 9 , 14 May 2022 , pp. 1313 - 1319
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Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of The Nutrition Society

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