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Basic science: (April 2009)

Published online by Cambridge University Press:  01 August 2009

R. Sutherland
Cancer Research ProgramGarvan Institute of Medical ResearchDarlinghurst, NSW, Australia


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Journals Watch
Copyright © Cambridge University Press 2009


1.Alli, E, Sharma, VB, Sunderesakumar, P, Ford, JM. Defective repair of oxidative DNA damage in triple-negative breast cancer confers sensitivity to inhibition of poly(ADP-ribose) polymerase. Cancer Res 2009; 69: 35893596.CrossRefGoogle ScholarPubMed
2.Andre, F, Michiels, S, Dessen, P, Scott, V, Suciu, V, Uzan, C, Lazar, V, Lacroix, L, Vassal, G, Spielmann, M, Vielh, P, Delaloge, S. Exonic expression profiling of breast cancer and benign lesions: a retrospective analysis. Lancet Oncol 2009; 10: 381390.CrossRefGoogle ScholarPubMed
3.Azuma, K, Urano, T, Horie-Inoue, K, Hayashi, S, Sakai, R, Ouchi, Y, Inoue, S. Association of estrogen receptor α and histone deacetylase 6 causes rapid deacetylation of tubulin in breast cancer cells. Cancer Res 2009; 69: 29352940.CrossRefGoogle ScholarPubMed
4.Barclay, JL, Anderson, ST, Waters, MJ, Curlewis, JD. SOCS3 as a tumor suppressor in breast cancer cells, and its regulation by PRL. Int J Cancer 2009; 124: 17561766.CrossRefGoogle ScholarPubMed
5.Cardamone, MD, Bardella, C, Gutierrez, A, Croce, LD, Rosenfeld, MG, Di Renzo, MF, De Bortoli, M. ERα as ligand-independent activator of CDH-1 regulates determination and maintenance of epithelial morphology in breast cancer cells. Proc Natl Acad Sci U S A 2009; 106: 74207425.CrossRefGoogle ScholarPubMed
6.Cheng, CJ, Lin, YC, Tsai, MT, Chen, CS, Hsieh, MC, Chen, CL, Yang, RB. SCUBE2 suppresses breast tumor cell proliferation and confers a favorable prognosis in invasive breast cancer. Cancer Res 2009; 69: 36343641.CrossRefGoogle ScholarPubMed
7.De Amicis, F, Zupo, S, Panno, ML, Malivindi, R, Giordano, F, Barone, I, Mauro, L, Fuqua, SAW, Ando, S. Progesterone receptor B recruits a repressor complex to a half-PRE site of the estrogen receptor α gene promoter. Mol Endocrinol 2009; 23: 454465.CrossRefGoogle ScholarPubMed
8.Delk, NA, Hunt, KK, Keyomarsi, K. Altered subcellular localization of tumor-specific cyclin E isoforms affects cyclin-dependent kinase 2 complex formation and proteasomal regulation. Cancer Res 2009; 69: 28172825.CrossRefGoogle ScholarPubMed
9.Gonzalez-Angulo, AM, Stemke-Hale, K, Palla, SL, Carey, M, Agarwal, R, Meric-Berstam, F, Traina, TA, Hudis, C, Hortobagyi, GN, Gerald, WL, Mills, GB, Hennessy, BT. Androgen receptor levels and association with PIK3CA mutations and prognosis in breast cancer. Clin Cancer Res 2009; 15: 24722478.CrossRefGoogle ScholarPubMed
10.Habermann, JK, Doering, J, Hautaniemi, S, Roblick, UJ, Bundgen, NK, Nicorici, D, Kronenwett, U, Rathnagiriswaran, S, Mettu, RKR, Ma, Y, Kruger, S, Bruch, HP, Auer, G, Guo, NL, Ried, T. The gene expression signature of genomic instability in breast cancer is an independent predictor of clinical outcome. Int J Cancer 2009; 124: 15521564.CrossRefGoogle ScholarPubMed
11.Kataoka, M, Antoniou, A, Warren, R, Leyland, J, Brown, J, Audley, T, Easton, D. Genetic models for the familial aggregation of mammographic breast density. Cancer Epidemiol Biomarkers Prev 2009; 18: 12771284.CrossRefGoogle ScholarPubMed
12.Kazi, A, Carie, A, Blaskovich, MA, Bucher, C, Thai, V, Moulder, S, Peng, H, Carrico, D, Pusateri, E, Pledger, WJ, Berndt, N, Hamilton, A, Sebti, SM. Blockade of protein geranylgeranylation inhibits Cdk2-dependent p27(Kip1) phosphorylation on Thr187 and accumulates p27(Kip1) in the nucleus: implications for breast cancer therapy. Mol Cell Biol 2009; 29: 22542263.CrossRefGoogle ScholarPubMed
13.Kwek, SS, Roy, R, Zhou, H, Climent, J, Martinez-Climent, JA, Fridlyand, J, Albertson, DG. Co-amplified genes at 8p12 and 11q13 in breast tumors cooperate with two major pathways in oncogenesis. Oncogene 2009; 28: 18921903.CrossRefGoogle ScholarPubMed
14.Mercier, I, Casimiro, MC, Zhou, J, Wang, C, Plymire, C, Bryant, KG, Daumer, KM, Sotgia, F, Bonuccelli, G, Witkiewicz, AK, Lin, J, Tran, TH, Milliman, J, Frank, PG, Jasmin, JF, Rui, H, Pestell, RG, Lisanti, MP. Genetic ablation of caveolin-1 drives estrogen-hypersensitivity and the development of DCIS-like mammary lesions. Am J Pathol 2009; 174: 11721190.CrossRefGoogle ScholarPubMed
15.Millar, EKA, Dean, JL, McNeil, CM, O’Toole, SA, Henshall, SM, Tran, T, Lin, J, Quong, A, Comstock, CES, Witkiewicz, A, Musgrove, EA, Rui, H, LeMarchand, L, Setiawan, VW, Haiman, CA, Knudsen, KE, Sutherland, RL, Knudsen, ES. Cyclin D1b protein expression in breast cancer is independent of cyclin D1a and associated with poor disease outcome. Oncogene 2009; 28: 18121820.CrossRefGoogle ScholarPubMed
16.Natrajan, R, Lambros, MB, Rodriguez-Pinilla, SM, Moreno-Bueno, G, Tan, DSP, Marchio, C, Vatcheva, R, Rayter, S, Mahler-Araujo, B, Fulford, LG, Hungermann, D, Mackay, A, Grigoriadis, A, Fenwick, K, Tamber, N, Hardisson, D, Tutt, A, Palacios, J, Lord, CJ, Buerger, H, Ashworth, A, Reis, JS. Tiling path genomic profiling of grade 3 invasive ductal breast cancers. Clin Cancer Res 2009; 15: 27112722.CrossRefGoogle ScholarPubMed
17.Neal, CL, Yao, J, Yang, WT, Zhou, XY, Nguyen, NT, Lu, J, Danes, CG, Guo, H, Lan, KH, Ensor, J, Hittelman, W, Hung, MC, Yu, DH. 14-3-3 ζ Overexpression defines high risk for breast cancer recurrence and promotes cancer cell survival. Cancer Res 2009; 69: 34253432.CrossRefGoogle Scholar
18.Nikkila, J, Coleman, KA, Morrissey, D, Pylkas, K, Erkko, H, Messick, TE, Karppinen, SM, Amelina, A, Winqvist, R, Greenberg, RA. Familial breast cancer screening reveals an alteration in the RAP80 UIM domain that impairs DNA damage response function. Oncogene 2009; 28: 18431852.CrossRefGoogle ScholarPubMed
19.Ohashi, E, Kogai, T, Kagechika, H, Brent, GA. Activation of the PI3 kinase pathway by retinoic acid mediates sodium/iodide symporter induction and iodide transport in MCF-7 breast cancer cells. Cancer Res 2009; 69: 34433450.CrossRefGoogle ScholarPubMed
20.Pitroda, SP, Khodarev, NN, Beckett, MA, Kufe, DW, Weichselbaum, RR. MUC1-induced alterations in a lipid metabolic gene network predict response of human breast cancers to tamoxifen treatment. Proc Natl Acad Sci U S A 2009; 106: 58375841.CrossRefGoogle Scholar
21.Plotnikov, A, Varghese, B, Tran, TH, Litt, CB, Rui, H, Fuchs, SY. Impaired turnover of prolactin receptor contributes to transformation of human breast cells. Cancer Res 2009; 69: 31653172.CrossRefGoogle ScholarPubMed
22.Rakha, EA, Elsheikh, SE, Aleskandarany, MA, Habashi, HO, Green, AR, Powe, DG, El-Sayed, ME, Benhasouna, A, Brunet, JS, Akslen, LA, Evans, AJ, Blamey, R, Reis, JS, Foulkes, WD, Ellis, IO. Triple-negative breast cancer: distinguishing between basal and nonbasal subtypes. Clin Cancer Res 2009; 15: 23022310.CrossRefGoogle ScholarPubMed
23.Santisteban, M, Reiman, JM, Asiedu, NK, Behrens, MD, Nassar, A, Kalli, KR, Haluska, P, Ingle, JN, Hartmann, LC, Manjili, MH, Radisky, DC, Ferrone, S, Knutson, KL. Immune-induced epithelial to mesenchymal transition in vivo generates breast cancer stem cells. Cancer Res 2009; 69: 28872895.CrossRefGoogle ScholarPubMed
24.Shackleton, M, O’Reilly, LA, Sutherland, KD, Bath, ML, Ellis, S, Strasser, A, Visvader, JE, Lindeman, GJ. Impaired lactation in mice expressing dominant-negative FADD in mammary epithelium. Dev Dyn 2009; 238: 10101016.CrossRefGoogle ScholarPubMed
25.Shephard, ND, Abo, R, Rigas, SH, Frank, B, Lin, WY, Brock, IW, Shippen, A, Balasubramanian, SP, Reed, MWR, Bartram, CR, Meindl, A, Schmutzler, RK, Engel, C, Burwinkel, B, Cannon-Albright, LA, Allen-Brady, K, Camp, NJ, Cox, A. A breast cancer risk haplotype in the caspase-8 gene. Cancer Res 2009; 69: 27242728.CrossRefGoogle ScholarPubMed
26.Wang, B, Mi, MT, Wang, J, Wei, N, Zhang, QY, Zhu, JD, Yang, S, Guo, BT, Xu, J, Yang, XH. Does the increase of endogenous steroid hormone levels also affect breast cancer risk in Chinese women? A case-control study in Chongqing, China. Int J Cancer 2009; 124: 18921899.CrossRefGoogle ScholarPubMed
27.Wang, MY, Chen, PS, Prakash, E, Hsu, HC, Huang, HY, Lin, MT, Chang, KJ, Kuo, ML. Connective tissue growth factor confers drug resistance in breast cancer through concomitant up-regulation of Bcl-xL and cIAP1. Cancer Res 2009; 69: 34823491.CrossRefGoogle ScholarPubMed
28.Workman, HC, Sweeney, C, Carraway, KL. The membrane mucin Muc4 inhibits apoptosis induced by multiple insults via ErbB2-dependent and ErbB2-independent mechanisms. Cancer Res 2009; 69: 28452852.CrossRefGoogle ScholarPubMed
29.Wua, M, Jung, L, Cooper, AB, Fleet, C, Chen, LH, Breault, L, Clark, K, Cai, ZH, Vincent, S, Bottega, S, Shen, Q, Richardson, A, Bosenburg, M, Naber, SP, DePinho, RA, Kuperwasserf, C, Robinson, MO. Dissecting genetic requirements of human breast tumorigenesis in a tissue transgenic model of human breast cancer in mice. Proc Natl Acad Sci U S A 2009; 106: 70227027.CrossRefGoogle Scholar
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Basic science: (April 2009)
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