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Psychopathology and cognitive deficits in young people exposed to complex trauma

Published online by Cambridge University Press:  18 June 2021

Stephanie J Lewis*
Affiliation:
Institute of Psychiatry, Psychology & Neuroscience, King's College London, South London and Maudsley NHS Foundation Trust
Karestan C Koenen
Affiliation:
Harvard TH Chan School of Public Health
Antony Ambler
Affiliation:
Institute of Psychiatry, Psychology and Neuroscience, King's College London
Louise Arseneault
Affiliation:
Institute of Psychiatry, Psychology and Neuroscience, King's College London
Avshalom Caspi
Affiliation:
Duke University, Institute of Psychiatry, Psychology and Neuroscience, King's College London
Helen L Fisher
Affiliation:
Institute of Psychiatry, Psychology and Neuroscience, King's College London
Terrie E Moffitt
Affiliation:
Duke University, Institute of Psychiatry, Psychology and Neuroscience, King's College London
Andrea Danese
Affiliation:
Institute of Psychiatry, Psychology & Neuroscience, King's College London, South London and Maudsley NHS Foundation Trust
*
*corresponding author.
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Abstract

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Aims

Complex traumas are traumatic experiences that involve multiple interpersonal threats during childhood or adolescence, such as repeated abuse. This type of trauma is hypothesized to lead to more severe psychopathology and poorer cognitive function than other non-complex traumas, such as road traffic accidents. However, empirical testing of this hypothesis has been limited to clinical or convenience samples and cross-sectional designs. To better understand this topic, we aimed to investigate psychopathology and cognitive function in young people exposed to complex, non-complex, or no trauma from a population-representative longitudinal cohort, and to consider the role of pre-existing vulnerabilities.

Method

Participants were from the Environmental Risk (E-Risk) Longitudinal Twin Study, a population-representative birth-cohort of 2,232 children born in England and Wales in 1994-95. At age 18 years (93% participation), we assessed lifetime exposure to complex and non-complex trauma. We also assessed past-year psychopathology including general psychopathology ‘p’ and several psychiatric disorders, as well as current cognitive function including IQ, executive function, and processing speed. Additionally, we prospectively assessed early childhood vulnerabilities including internalizing and externalizing symptoms at age 5, IQ at age 5, family history of mental illness, family socioeconomic status, and sex.

Result

We found that participants who had been exposed to complex trauma had more severe psychopathology and poorer cognitive function across wide-ranging measures at age 18, compared to both trauma-unexposed participants and those exposed to non-complex trauma. Early childhood vulnerabilities had an important role in these presentations, as they predicted risk of later complex trauma exposure, and largely explained associations of complex trauma with cognitive deficits, but not with psychopathology.

Conclusion

By conflating complex and non-complex traumas, current research and clinical practice under-estimate the severity of psychopathology and cognitive deficits linked with complex trauma, as well as the role of pre-existing vulnerabilities. A better understanding of the mental health needs of people exposed to complex trauma and underlying mechanisms could inform the development of new effective interventions.

Type
Rapid-Fire Poster Presentations
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press on behalf of the Royal College of Psychiatrists
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