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Predictive Factors in the Treatment of Obsessive-Compulsive Disorders with Fluvoxamine and/or Behaviour Therapy

Published online by Cambridge University Press:  16 June 2009

Jean Cottraux ,
Philippe Messy ,
Isaac M. Marks ,
Evelyne Mollard  and
Martine Bouvard
Jean Cottraux
Affiliation:
Université of Lyon, France
Philippe Messy
Affiliation:
Hospices Civils de Lyon, France
Isaac M. Marks
Affiliation:
Institute of Psychiatry, London
Evelyne Mollard
Affiliation:
Hopital Neurologique, Lyon, France
Martine Bouvard
Affiliation:
Hopital Neurologique, Lyon, France
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Extract

Fisher's stepwise discriminant analysis was carried out on 10 baseline variables searching for posterior prediction of success in a sample of sixty DSM-III obsessive-compulsive patients. The patients' median score on Hamilton rating scale of depression was 19. In a controlled study they were randomized into three groups: fluvoxamine with antiexposure, fluvoxamine with exposure, or placebo with exposure. In the whole sample, five variables accounted for 76% of the correctly classified patients: avoidance score of the behavioural avoidance test, behaviour therapy expectations, fluvoxamine expectations, Beck depression inventory and rituals repetition. High avoidance score predicted 68% of the correctly classified patients in the whole sample. The discriminant function classified correctly 70% of the patients in the antiexposure with fluvoxamine group, versus 75% in the exposure with fluvoxamine group, and 85% of the patients receiving exposure with placebo (χ2, d.f.2, NS).

Type
Research Article
Information
Behavioural and Cognitive Psychotherapy , Volume 21 , Issue 1 , January 1993 , pp. 45 - 50
Copyright
Copyright © British Association for Behavioural and Cognitive Psychotherapies 1993

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