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Polygene risk scores and randomized experiments

Published online by Cambridge University Press:  11 September 2023

Lauren N. Ross
Affiliation:
Logic and Philosophy of Science Department, University of California-Irvine, Irvine, CA, USA rossl@uci.edu https://www.lps.uci.edu/~rossl/
Kenneth S. Kendler
Affiliation:
Virginia Institute for Psychiatric and Behavioral Genetics and Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA kenneth.kendler@vcuhealth.org https://vipbg.vcu.edu/people/kenneth-kendler/
James F. Woodward
Affiliation:
Department of History and Philosophy of Science, University of Pittsburgh, Pittsburgh, PA, USA jfw@pitt.edu https://jameswoodward.org

Abstract

We explore Madole & Harden's (2022) suggestion that single-nucleotide polymorphism (SNP)/trait correlations are analogous to randomized experiments and thus can be given a causal interpretation.

Type
Open Peer Commentary
Copyright
Copyright © The Author(s), 2023. Published by Cambridge University Press

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References

Kendler, K., & Woodward, J. (under review). Polygene risk scores: A philosophical exploration.Google Scholar