Published online by Cambridge University Press: 21 September 2001
Robert Koch (1843–1910) discovered the causal agents for tuberculosis, cholera, and anthrax. The 1905 Nobel Prize acknowledged Koch's criteria for identifying the causal agent of an infectious disease. These criteria remain useful and the data reviewed below show that the cholinergic contributions to REM sleep control are confirmed by Koch's postulates.
[Hobson et al.]