Effect of Fish on the Human Heart is a book in a box produced collaboratively by three individuals who, at the start of the project in Spring 1990, were all employed in the National Gallery of Art Library, Washington, D.C. The book was written and produced in an edition of twenty copies by Alfred Willis. It features a frontispiece by Susan Clay, and Roger Lawson participated in the design and construction of the book’s box. The matt black box, produced in an edition of twelve copies, incorporates two niches, one containing a basswood fish sculpted and painted by Clay, the other containing the book. The book is secured in its niche by a fishhook which swivels on a brass screw to permit its removal.