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Parent-of-origin effects cause genetic variation in pig performance traits

Published online by Cambridge University Press:  08 January 2010

N. Neugebauer ,
H. Luther  and
N. Reinsch
N. Neugebauer
Affiliation:
Forschungsinstitut für die Biologie landwirtschaftlicher Nutztiere, FBN, Forschungsbereich Genetik und Biometrie, Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany
H. Luther
Affiliation:
SUISAG, AG für Dienstleistungen in der Schweineproduktion, Allmend, CH-6204 Sempach, Switzerland
N. Reinsch*
Affiliation:
Forschungsinstitut für die Biologie landwirtschaftlicher Nutztiere, FBN, Forschungsbereich Genetik und Biometrie, Wilhelm-Stahl-Allee 2, 18196 Dummerstorf, Germany
*
†E-mail: reinsch@fbn-dummerstorf.de
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Abstract

In order to assess the relative importance of genomic imprinting for the genetic variation of traits economically relevant for pork production, a data set containing 21 209 records from Large White pigs was analysed. A total of 33 traits for growth, carcass composition and meat quality were investigated. All traits were recorded between 1997 and 2006 at a test station in Switzerland and the pedigree included 15 747 ancestors. A model with two genetic effects for each animal was applied: the first corresponds to a paternal and the second to a maternal expression pattern of imprinted genes. The imprinting variance was estimated as the sum of both corresponding genetic variances per animal minus twice the covariance. The null hypothesis of no imprinting was tested by a restricted maximum likelihood ratio test with two degrees of freedom. Genomic imprinting significantly contributed to the genetic variance of 19 traits. The proportion of the total additive genetic variance that could be attributed to genomic imprinting was of the order between 5% and 19%.

Keywords

genomic imprinting, epigenetics, variance components, imprinting variance, carcass and growth traits in pigs
Type
Full Paper
Information
animal , Volume 4 , Issue 5 , May 2010 , pp. 672 - 681
Copyright
Copyright © The Animal Consortium 2009

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