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An assessment of laboratory mouse welfare in UK animal units

Published online by Cambridge University Press:  11 January 2023

MC Leach  and
DCJ Main
MC Leach*
Affiliation:
University of Newcastle upon Tyne, Comparative Biology Centre, Framlington Place, Newcastle upon Tyne NE2 4HH, UK
DCJ Main
Affiliation:
University of Bristol, Department of Clinical Veterinary Science, Langford House, Langford, Bristol BS40 5DU, UK
*
* Contact for correspondence and requests for reprints: m.c.leach@ncl.ac.uk
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Abstract

The welfare of conventional stock laboratory mice has been assessed in 46 UK animal units using an expert-defined welfare assessment protocol containing 119 measures of mouse welfare. These were recorded using a questionnaire and observations made during a one-day visit to each unit. The standard of mouse welfare was considered to be good with widespread use of substrate and nesting material and space allowances in most cases well above the minimum recommended levels. Education and training was available and encouraged by the majority of animal units. The health and welfare of laboratory mice was being frequently assessed by animal care staff using daily inspections/observations, health records, and health monitoring schemes. Overall the mice assessed could be considered to be in good health, as indicators of poor health and welfare were exhibited at low levels, and the mice were observed exhibiting a wide range of positive natural behaviours. A number of environmental conditions (humidity, noise and light intensity) were outside recommended ranges in some animal units. The provision of cage resources such as shelters, gnawing material, floor food and other enrichment items were found to be variable. A high proportion of the units surveyed housed at least some of their mice (mainly males) singly and handling of mice by care staff varied between units. In some units there may be an opportunity for some staff to improve in some aspects of mouse handling. Finally, a number of interesting correlations were found between various behaviours and potential indictors of abnormal health or welfare, which require further investigation.

Keywords

animal-based outcome measuresanimal welfareassessmentlaboratory miceresource-input measuresUK animal units
Type
Articles
Information
Animal Welfare , Volume 17 , Issue 2 , May 2008 , pp. 171 - 187
Copyright
© 2008 Universities Federation for Animal Welfare

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