Hostname: page-component-8448b6f56d-m8qmq Total loading time: 0 Render date: 2024-04-25T05:52:45.959Z Has data issue: false hasContentIssue false

Effects of oestradiol-17β or zeranol with or without trenbolone acetate on live-weight gain, carcass composition and zeranol residues in steers on an 18-month beef system

Published online by Cambridge University Press:  02 September 2010

J. R. Southgate
Affiliation:
Meat and Livestock Commission, PO Box 44, Queensway House, Bletchley, Milton Keynes MK2 2EF
A. R. Peters
Affiliation:
British Technology Group, 101 Newington Causeway, London SE1 6BU
S. N. Dixon
Affiliation:
Food and Veterinary Laboratory Ltd, 25-26 Frederick Sanger Road, Surrey University Park, Guildford GU2 5YD
Get access

Abstract

A comparison of anabolic treatment regimes was made in 761 autumn-born Friesian steers on 14 farms. Prior to turn-out for grazing at 6 months of age and approximately 180 kg live weight, steers were weighed and divided into three equal-weight groups. Group 1 received silastic implants containing 45 mg oestradiol-17β. Group 2 received 36 mg zeranol and group 3 were untreated controls. All steers were weighed at intervals of approximately 3 months (i.e. mid summer, yarding at autumn, mid winter and pre-slaughter) and group 2 steers received a further 36 mg zeranol at the second, third and fourth weighing. At the third weighing half the cattle in each of the treatment groups 1 and 2 received 300 mg trenbolone acetate. Also at the third weighing, group 3 (controls) were subdivided into three equal-weight groups, the first of which received 45 mg oestradiol-17β and 300 mg trenbolone acetate and the second 36 mg zeranol and 300 mg trenbolone acetate. The third subgroup remained as untreated controls.

From 10 farms a 25% sample close to group mean weight at mid winter were slaughtered on the same day and subjectively assessed for subcutaneous fat score and conformation on 15-point scales. The left thin flank was separated into tissues. Samples of lean fat, liver and kidney were analysed for zeranol residues. All implant treatments resulted in higher live-weight gain, heavier slaughter weights and earlier slaughter. Trenbolone increased daily gain only during the first 3 months after treatment. Implanted carcasses were heavier both in the fore- and hindquarter but trenbolone also produced heavier forequarters. Carcasses from treated steers had more subcutaneous fat, less perinephric and retroperitoneal fat and less intermuscular fat in the thin-flank joint. Zeranol residues in implanted steers were not significantly higher than controls except in the kidney, but even these were significantly below accepted tolerance levels.

Type
Research Article
Copyright
Copyright © British Society of Animal Science 1988

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Allen, D. and Kilkenny, B. 1980. Planned Beef Production. Granada, London.Google Scholar
Buttery, P. J. and Sinnett-Smith, P. A. 1984. The mode of action of anabolic agents with special reference to their effects on protein metabolism — some speculations. In Manipulation of Growth in Farm Animals (ed. Roche, J. F. and O'Callaghan, D.), pp. 211228. Martinus Nijhoff, The Hague.CrossRefGoogle Scholar
Dixon, S. N.Radioimmunoassay of the anabolic agent zeranol. IV. The determination of zeranol concentrations in the edible tissues of cattle implanted with zeranol (Ralgro). Journal of Veterinary Pharmacology and Therapeutics 9: 94100.CrossRefGoogle Scholar
Galbraith, H. and Topps, T. H. 1981. Effects of hormones on the growth and body composition of animals. Nutrition Abstracts and Reviews, Series B 51: 521540.Google Scholar
Hoffmann, B. 1983. Natural occurrence of steroid hormones in food producing animals. In Anabolics in Animal Production (ed. Meissonier, E. and MitchellVigneron, J.), pp. 215231. Office International des Epizooties, Paris.Google Scholar
Lamming, G. E., Ballarini, G., Baulieu, E. E., Brookes, P., Elias, P. S., Ferrando, R., Galli, C. L., Heitzman, R. J., Hoffman, B., Karg, H., Meyer, H. H. D., Michel, G., Poulsen, E., Rico, A., Leeuwen, F. X. R. van and White, D. S. 1987. Scientific report on anabolic agents in animal production. Veterinary Record 121: 389392.Google Scholar
Peters, A. R., Southgate, J. R., Aughey, E. and Dixon, S. N. 1987. The effect of oestrogenic agents on live-weight gain, carcass composition, reproductive function and tissue residues in intensively reared beef bulls given cereal-based diets. Animal Production 47: 215221.Google Scholar
Roche, J. F. and Quirke, J. F. 1986. The effects of steroid hormones and xenobiotics on growth of farm animals. In Control and Manipulation of Animal Growth (ed. Buttery, P. J., Haynes, N. B. and Lindsay, D. B.), pp. 3951. Butterworths, London.CrossRefGoogle Scholar
Van der Wai, P. and Berende, P. L. M. 1983. Effects of anabolic agents on food-producing animals. In Anabolics in Animal Production (ed. Meissonier, E. and Mitchell-Vigneron, J.), pp. 73115. Office International des Epizooties, Paris.Google Scholar