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Plasma Lipid Variability in the Toronto Twin Register

Published online by Cambridge University Press:  01 August 2014

Jean Milner*
Affiliation:
Department of Preventive Medicine and Biostatistics, University of Toronto
Joe C. Christian
Affiliation:
Department of Medical Genetics, Indiana University School of Medicine, Indianapolis
David Hewitt
Affiliation:
Department of Preventive Medicine and Biostatistics, University of Toronto
*Corresponding
Department of Preventive Medicine and Biostatistics, University of Toronto, Toronto, Canada M5S 1A8

Abstract

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Plasma lipids were studied on 92 pairs of twins (66 MZ and 26 like-sexed DZ). The DZ twins had significantly greater total variance than the MZ twins for total plasma cholesterol but not for triglycerides or the high, low, and very low-density lipoprotein cholesterol fractions.

Type
Short Note
Copyright
Copyright © The International Society for Twin Studies 1980

References

1. Christian, JC, Kang, KW, Norton, JA Jr (1974. Choice of an estimate of genetic variance from twin data. Am J Hum Genet 26:154161.Google Scholar
2. Christian, JC, Feinleib, M, Hulley, SB, Castelli, WP, Fabsitz, RR, Garrison, RJ, Borhani, NO, Rosenman, RH, Wagner, J (1976. Genetics of plasma cholesterol and triglycerides: A study of adult male twins. Acta Genet Med Gemellol 25:145149.CrossRefGoogle ScholarPubMed
3. Christian, JC, Kang, KW, Nance, WE (1976): Plasma cholesterol in newborn human twins. J Am Oil Chem 52:123.Google Scholar
4. Christian, JC, Norton, JA Jr (1977. A proposed test of the difference between the means of monozygotic and dizygotic twins. Acta Genet Med Gemellol 26:4954.CrossRefGoogle ScholarPubMed
5. Corey, LA, Kang, KW, Christian, JC, Norton, JA Jr, Harris, RE, Nance, WE (1976. Effects of variation in cord blood cholesterol of monozygotic twins. Am J Hum Genet 28:433441.Google ScholarPubMed
6. Hewitt, D, Jones, GJL, Godin, GJ, McComb, K, Breckenridge, WC, Little, JA, Steiner, G, Mishkel, MA, Baillie, JH, Martin, RH, Gibson, ES, Prendergast, WF, Parliament, WJ (1977. Normative standards of plasma cholesterol and triglyceride concentrations in Canadians of working age. Can Med Assoc J 117:10201024.Google Scholar
7. Lipid Research Clinics Program (1974): Lipid and Lipoprotein Analysis. National Health Institute Publication 75678. Washington, DC: US Dept Health, Education and Welfare, vol 1.Google ScholarPubMed
8. Uchida, IA, Feinleib, M, Christian, JC (1980): Comparisons of coronary heart disease risk factors in monozygotic and dizygotic twins. Third International Congress on Twin Studies, Jerusalem.Google Scholar
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