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Optimization Procedures in Twin Zygosity Diagnosis by Genetic Markers. A Cost-Effectiveness Analysis

Published online by Cambridge University Press:  01 August 2014

Seppo Sarna*
Affiliation:
Department of Public Health Science, University of Helsinki
Jaakko Kaprio
Affiliation:
Department of Public Health Science, University of Helsinki
*
Department of Public Health Science, Haartmaninkatu 3, SF-00290 Helsinki 29, Finland

Abstract

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More and more genetic markers usable for twin zygosity determination have become available. A relatively small number of markers is sufficient to achieve a satisfactory probability of correctly classifying a twin pair. Previously only the genetic properties of markers have been considered when choosing the markers to be determined. A cost-effectiveness analysis, which considers both genetic properties and relative determination costs of markers, is presented and illustrated with data from the Finnish Twin Registry studies.

Type
Research Article
Copyright
Copyright © The International Society for Twin Studies 1979

References

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Optimization Procedures in Twin Zygosity Diagnosis by Genetic Markers. A Cost-Effectiveness Analysis
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