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Holzinger's HC Revised
Published online by Cambridge University Press: 01 August 2014
Abstract
The formula H′C = 1 − CDZ/CMZ is suggested as a better summary of twin concordance data than the familiar Holzinger concordance formula, HC = (CMZ − CDZ)/ (1 − CDZ). The new formula better estimates degree of genetic determination, G, as calculated from a threshold model, but never exceeds unity, as G sometimes does. For high concordance rates, if CMZ + CDZ > 1, HC, may be more useful than either G or H′C.
- Type
- Research Article
- Information
- Acta geneticae medicae et gemellologiae: twin research , Volume 28 , Issue 2 , April 1979 , pp. 161 - 164
- Copyright
- Copyright © The International Society for Twin Studies 1979
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