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Concordant primary atrophy of the cerebellar granules in monozygotic twins

Published online by Cambridge University Press:  01 August 2014

Summary

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The case is described of monozygotic twins similarly affected with a form of cerebellar atrophy characterized by primary lesions of the granular layer. The clinical and pathologic aspects of the disease are briefly discussed and the role of genetic factors in the determination of the condition emphasized.

Type
Research Article
Copyright
Copyright © The International Society for Twin Studies 1954

References

1. Norman, R. M.: Primary Degeneration of the Granular Layer of the Cerebellum. An Unusual Form of Familial Cerebellar Atrophy Occurring in Early Life. Brain, 63: 365, 1940.Google Scholar
2. Ule, G.: Kleinhirnatrophie vom Körnertyp. Deut. Ztsch. f. Nervenk., 168: 195, 1952.Google Scholar
3. Jervis, G. A.: Early Familial Cerebellar Degeneration. Report of Three Cases in One Family. J. Nerv, and Ment. Dis., 111: 398, 1950.Google Scholar
4. Vogt, H. and Astwazaturow, M.: Ueber angeborene Kleinhirnerkrankungen mit Beiträgen zur Entwickelungsgeschichte des Kleinhirns. Arch. f. Psychiat., 49: 75, 1912.Google Scholar
5. Schob, F.: Weitere Beiträge zur Kenntnis der Friedreichähnlichen Krankheitsbilder. Ztschr. f. d. ges. Neur. u. Psychiat., 73: 188, 1921.Google Scholar
6. Scherer, H. J.: Beiträge zur pathologischen Anatomie des Kleinhirns. Ztschr. f. d. ges. Neurol. u. Psychiat., 145: 335, 1933.Google Scholar
7. Santha, K.: Ueber das Verhalten des Kleinhirns in einem Falle von endogenen-afamiliarer Idiotie. Ztschr. f. d. ges. Neurol. u. Psychiat., 123: 717, 1930.CrossRefGoogle Scholar
8. Welte, E.: Die Atrophie der Systems des Brückenfusse und der untern Oliven. Arch. f. Psychiat. u. Nervenk., 109: 649, 1939.Google Scholar
9. Sjögren, T.: Klinische und erbbiologische Untersuchungen ueber die Heredoataxien. Acta Psychiat. et Neur. Suppl. 27, 1943.Google Scholar
10. Gedda, L.: Studio dei Gemelli. Ed. Orizzonte Medico, Roma, 1951.Google Scholar
11. Upners, T.: Experimentelle Untersuchungen ueber die lokale Einwirkung des Thiopens im Zentralnervensystem. Ztschr. f. d. ges. Neurol. u. Psychiat., 166: 623, 1939.Google Scholar
12. Leigh, A. D. and Meyer, A.: Degeneration of the Granular Layer of the Cerebellum. J. of Neurol. and Psychiat., 12: 287, 1949.CrossRefGoogle ScholarPubMed
13. Jervis, G. A.: Mental Deficiency and Aberrant Metabolism in The Biology of Mental Health and Disease, p. 422, Hoeber, New York, 1952.Google Scholar