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Acardius in a Triplet Pregnancy: Cytogenetic and Morphological Profile

Published online by Cambridge University Press:  01 August 2014

I.I. Bolaji
Affiliation:
Departments of Obstetrics and Gynaecology
G. Mortimer*
Affiliation:
Departments of Pathology, University College Hospital, Galway, Ireland
F.P. Meehan
Affiliation:
Departments of Obstetrics and Gynaecology
S. England
Affiliation:
Departments of Pathology, University College Hospital, Galway, Ireland
M. Greally
Affiliation:
Departments of Obstetrics and Gynaecology
*
Department of Pathology, University College Hospital, Galway, Ireland

Abstract

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We describe a rare case of acardius in a triplet pregnancy terminated by Caesarean Section at 32 weeks gestation. Morphological and chromosomal abnormalities of the fetus as well as structural abnormalities of the placenta are presented. Cytogenetic analysis and examination of the single disc triplet placenta provide evidence for the two major theories of pathogenesis of acardius, the twin reversed arterial perfusion (TRAP) sequence and the genetic theory, which we believe are not necessarily mutually exclusive.

Type
Research Article
Copyright
Copyright © The International Society for Twin Studies 1992

References

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