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Composition of Coal Dusts and Their Cytotoxicity on Alveolar Macrophages

Published online by Cambridge University Press:  06 March 2019

C. Y. Lee ,
S.L Lee ,
C. E. Sheehan  and
Yinghua Wang
C. Y. Lee
Affiliation:
Stratton VA Medical Center and Albany Medical College, Department of Pathology and Laboratory Medicine, Albany, NY 12208
S.L Lee
Affiliation:
US Army Armament Research Development and Engineering Center, Benet Laboratories, Watervliet, NY 12189-4050.
C. E. Sheehan
Affiliation:
Stratton VA Medical Center and Albany Medical College, Department of Pathology and Laboratory Medicine, Albany, NY 12208
Yinghua Wang
Affiliation:
Stratton VA Medical Center and Albany Medical College, Department of Pathology and Laboratory Medicine, Albany, NY 12208
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Abstract

Coal mine dust is produced from complex materials which consist of organic sedimentary phases, inorganic minerals, and trace elements. The dust varies in its chemical compositions and is capable of causing lung injury when inhaled. The purpose of this study was to perform scanning electron microscopy combined with energy dispersive spectrometry, wavelength dispersive spectrometry and X-ray diffraction analyses of three coal dusts and examine their effects on rat lung alveolar macrophages (AM) in cell culture. The coal dusts were obtained from coal surfaces of anthracite, meager and fat coal mines. AM were harvested by bronchoalveolar lavage from adult male Wistar rats and were cultured in Eagle's medium at 37°C.

Type
Research Article
Information
Advances in X-Ray Analysis , Volume 39: Forty-Fourth Annual Conference on Applications of X-ray Analysis, July 31 - August 4, 1995 , 1995 , pp. 561 - 569
Copyright
Copyright © International Centre for Diffraction Data 2002

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