Hostname: page-component-76fb5796d-45l2p Total loading time: 0 Render date: 2024-04-28T02:17:23.469Z Has data issue: false hasContentIssue false
  • English
  • Français

Korsakoff's syndrome on the MMPI-2

Published online by Cambridge University Press:  24 June 2014

Jos I. M. Egger ,
Arie J. Wester ,
Hubert R. A. De Mey  and
Jan J. L. Derksen
Jos I. M. Egger*
Affiliation:
University of Nijmegen, Nijmegen, the Netherlands Vincent van Gogh Institute for Psychiatry, Venray, the Netherlands
Arie J. Wester
Affiliation:
Vincent van Gogh Institute for Psychiatry, Venray, the Netherlands
Hubert R. A. De Mey
Affiliation:
University of Nijmegen, Nijmegen, the Netherlands
Jan J. L. Derksen
Affiliation:
University of Nijmegen, Nijmegen, the Netherlands
*
Jos I.M. Egger, Department of Clinical Psychology and Personality, University of Nijmegen, PO Box 9104, 6500 HE Nijmegen, the Netherlands. Tel: + 31 (0) 24 3612668; Fax: + 31 (0) 478 630797; E-mail: jegger@baserv.uci.kun.nl
Get access Rights & Permissions [Opens in a new window]

Abstract

Background:

This article describes an exploratory study of MMPI-2 administration to 20 patients with Korsakoff's disease, all admitted to the Korsakoff unit of a major psychiatric hospital in the Netherlands.

Methods:

We compared their MMPI-2 basic profiles with those of an inpatient alcohol-dependent non-Korsakoff group. Attention was also given to content scales and some selected supplementary scales. Furthermore, we explored the differences between MMPI-2 profiles of Korsakoff patients with and without insight into oneself and one's disease.

Results:

Compared with both the Dutch norms and the scale means of the non-Korsakoff alcoholics, Korsakoff patients showed an extraordinary flat profile. Illness insight appeared to be related to the levels of the various scales.

Discussion:

The results show the potential usefulness of the MMPI-2 in the differential diagnosis of chronic alcoholism and Korsakoff's disease.

Keywords

chronic alcoholismKorsakoffMMPI-2neuropsychiatric disorderspsychological assessmentpsychological profile
Type
Original Article
Information
Acta Neuropsychiatrica , Volume 14 , Issue 5 , October 2002 , pp. 231 - 236
Copyright
Copyright © Acta Neuropsychiatrica 2002

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Korsakow, SS. Psychosis polyneuritica sum cerebropathia psychica toxaemica. Medizinskoje Obozrenije 1889: 31. Google Scholar
Kopelman, MD. The Korsakoff syndrome. Br J Psychiatry 1995;166: 154–173.CrossRefGoogle ScholarPubMed
Plutchik, R, Discipio, WJ. Personality patterns in chronic alcoholism (Korsakoff's syndrome), chronic schizophrenia, and geriatric patients with chronic brain syndrome. J Am Geriatr Soc 1974;22: 514–516.CrossRefGoogle Scholar
Plomin, R, McClearn, GE, eds. Nature, Nurture and Psychology. Washington DC: American Psychological Association, 1993. CrossRefGoogle Scholar
Kirkpatrick, BRyan, WG. At issue: a default analysis for schizophrenia research. Schizophr Bull 2000;26: 157–161.CrossRefGoogle ScholarPubMed
Ben-Porath, YSButcher, JNGraham, JR. Contribution of the MMPI-2 content scales to the differential diagnosis of schizophrenia and major depression. Psychol Assessm 1991;3: 634–640. CrossRefGoogle Scholar
Delisi, LE. A new classification for the psychoses? Arch General Psychiatry 1999;56: 672. CrossRefGoogle ScholarPubMed
Butters, N. Alcoholic Korsakoff's syndrome: Some unresolved issues concerning etiology, neuropathology, and cognitive deficits. J Clin Exp Neuropsychol 1985;7: 181–210.CrossRefGoogle Scholar
APA. Diagnostic and Statistical Manual of Mental Disorders, 4th edn. Washington DC: American Psychiatric Association, 1994. Google ScholarPubMed
Eyskens, E, Feenstra, L, Meinders, AE, Vandenbroucke, JP. Codex Medicus, 9th edn. Arnhem: Elsevier, 1991. Google Scholar
NIGZ. Alcohol en de Hersenen [Alcohol and the Brain]. Worden: Dutch Institute for Health Prevention (NIGZ), 1999. Google Scholar
Victor, M, Adams, RD, Collins, GH. The Wernicke–Korsakoff Syndrome and Related Neurological Disorders due to Alcoholism and Malnutrition. Philadelphia: F.A. Davis, 1989. Google Scholar
Blansjaar, BA, Vielvoye, GJ, Van Dijk, JG, Rijnders, RJ. Similar brain lesions in alcoholics and Korsakoff patients: MRI, psychometric and clinical findings. Clin Neurol Neurosurg 1992;94: 197–203.CrossRefGoogle ScholarPubMed
Blansjaar, BA. Het syndroom van Korsakoff [Korsakoff's syndrome]. Ndl Tijdschr Geneeskd 1993;137: 1043–1048. Google Scholar
Ganzevles, PG J, De Geus, BW J, Wester, AJ. Cognitive and behavioral aspects of Korsakoff's syndrome: the effect of special Korsakoff wards in a general psychiatric hospital. Tijdschr Alcohol Drugs Andere Psychotrope Stoffen 1994;20: 20–31. Google Scholar
Blansjaar, BA, Takens, H, Zwinderman, Ah. The course of alcohol amnestic disorder: a three-year follow-up study of clinical signs and social disabilities. Acta Psychiatr Scand 1992;86: 240–246.CrossRefGoogle ScholarPubMed
NZI. Statistics on Psychiatric Hospitals in the Netherlands. Utrecht, Nederlands: Ziekenhuis Instituut, 1992. Google ScholarPubMed
Butcher, JN, Dahlstrom, WG, Graham, JR, Tellegen, A, Kaemmer, B. Minnesota Multiphasic Personality Inventory (MMPI-2): Manual for Adminstration and Scoring. Minneapolis: University of Minnesota Press, 1989. Google Scholar
Derksen, JJ L, De Mey, HR A, Sloore, H, Hellenbosch, G. MMPI-2: Handleiding Bij Afname, Scoring En Interpretatie, 3rd edn. Nijmegen: PEN Test Publisher 1997. Google Scholar
Johnson, RS, Tobin, JW, Cellucci, T. Personality characteristics of cocaine and alcohol abusers: more alike than different. Addictive Behav 1992;17: 159–166. CrossRefGoogle ScholarPubMed
Nace, EP, Davis, CW, Gaspari, JP. Axis II comorbidity in substance abusers. Am J Psychiatry 1991;148: 118–120.Google Scholar
Butcher, JN, Williams, CL. Essentials of MMPI-2 and MMPI-A Interpretation. Minneapolis: University of Minnesota Press 1998. Google Scholar
Alfano, DP, Finlayson, MA, Stearns, GM, Neilson, PM. The MMPI and neurologic dysfunction. profile configuration and analysis. Clin Neuropsychol 1990;4: 69–79. CrossRefGoogle Scholar
Cripe, LI, Dodrill, CB. Neuropsychological test performances with chronic low-level formaldehyde exposure. Clin Neuropsychol 1988;2: 41–48. CrossRefGoogle Scholar
De Mey, HR A, Derksen, JJ L. The new ‘uniform’ of the MMPI-2: about T-scores. Gedrag Gezondheid 1995;23: 179–184. Google Scholar
MacAndrew, C. The differentiation of male alcoholic outpatients from nonalcoholic inpatients by means of the MMPI. Quart J Studies Alcohol 1965;26: 43–51. Google Scholar
Preng, KW, Clopton, JR. The MacAndrew Scale: clinical application and theoretical issues. J Studies Alcohol 1986;47: 228–236. CrossRefGoogle ScholarPubMed
Preng, KW, Clopton, JR. Application to the MacAndrew Alcoholism Scale to alcoholics with psychiatric diagnoses. J Personal Assessm 1986;50: 113–122. CrossRefGoogle ScholarPubMed
Weed, NC, Butcher, JN, McKenna, T, Ben Porath, YS. New measures for assessing alcohol and drug abuse with the MMPI-2. The APS and AAS. J Personal Assessm 1992;58: 389–404. CrossRefGoogle Scholar
Greene, RL, Weed, NC, Butcher, JN, Arredondo, R, Davis, HG. A cross-validation of MMPI-2 substance abuse scales. J Personal Assessm 1992;58: 405–410. CrossRefGoogle ScholarPubMed
Theuns, P, De Mey, HR A, Schaeks, HM J, Bögels, T, Roverts, A, Derksen, JJ L. MMPI-2. Computer Program for Administration and Scoring. Nijmegen: PEN Test Publisher 1994. Google Scholar
Marks, PA, Seeman, W. An Atlas for Use with the MMPI. Actuarial Description of Abnormal Personality. Baltimore: Williams & Wilkins, 1963. Google Scholar
Schippers, GM, Lammers, SM M, Schaap, CPDR, eds. Contributions to the Psychology of Addiction. Lisse: Swets and Zeitlinger, 1991. Google Scholar
Graham, JR, Ben-Porath, YS, McNulty, JL. MMPI-2 Correlates for Outpatient Community Mental Health Settings. Minneapolis: University of Minnesota Press 1999. Google Scholar
Graham, JR. MMPI-2. Assessing Personality and Psychopathology, 2nd edn. New York: Oxford University Press 1993. Google Scholar
Cummings, JL. Frontal-subcortical circuits and human behavior. Arch Neurol 1993;50: 873–880.CrossRefGoogle ScholarPubMed
Cummings, JL. Principles of neuropsychiatry: towards a neuropsychiatric epistemology. Neurocase 1999;5: 181–188. CrossRefGoogle Scholar