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Drug-induced psychosis in Parkinson's disease (I): manifestations and therapy

Published online by Cambridge University Press:  18 September 2015

E.CH. Wolters ,
G. Tissingh ,
M.A. Kuiper ,
W.A. Zwaan  and
M.W.I.M. Horstink
E.CH. Wolters*
Affiliation:
Afdeling Neurologie, Academisch Ziekenhuis der Vrije Universiteit
G. Tissingh
Affiliation:
Afdeling Neurologie, Academisch Ziekenhuis der Vrije Universiteit
M.A. Kuiper
Affiliation:
Afdeling Neurologie, Academisch Ziekenhuis der Vrije Universiteit
W.A. Zwaan
Affiliation:
Afdeling Psychiatrie, Academisch Ziekenhuis der Vrije Universiteit
M.W.I.M. Horstink
Affiliation:
Afdeling neurologie, 3, Academisch Ziekenhuis Nijmegen
*
Postbus 7057, 1007 MB Amsterdam, Tel. 020-5482818
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Summary

In this first part of a review on drug-induced psychosis in Parkinson's disease, the etiology, the clinical features and the therapeutic strategies will be discussed. The drugs used in the therapy of Parkinson's disease may lead to non-motor complications, such as delirium or hallucinations. Especially anti-cholinergics, respectivily dopaminometics, play an important role. Lowering the dose or even discontinuing the medication is the main therapeutic measure. The use of an atypical antipsychotic drug (clozapine) may be indicated.

Keywords

Parkinson's diseaseorganic mental disordersanticholinergicsdopamineatypical neurolepticsziekte van Parkinsonorganische Psychosyndromenanticholinergicadopamineatypische neuroleptica
Type
Research Article
Information
Acta Neuropsychiatrica , Volume 6 , Issue 2 , June 1994 , pp. 29 - 33
Copyright
Copyright © Scandinavian College of Neuropsychopharmacology 1994

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References

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