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Cognitive and affective theory of mind in Korsakoff’s syndrome

Published online by Cambridge University Press:  18 December 2018

Rolinda Drost*
Affiliation:
Experimental Psychology, Helmholtz Institute, Utrecht University, Utrecht, The Netherlands Slingedael Korsakoff Center, Rotterdam, The Netherlands
Albert Postma
Affiliation:
Experimental Psychology, Helmholtz Institute, Utrecht University, Utrecht, The Netherlands Slingedael Korsakoff Center, Rotterdam, The Netherlands
Erik Oudman
Affiliation:
Experimental Psychology, Helmholtz Institute, Utrecht University, Utrecht, The Netherlands Slingedael Korsakoff Center, Rotterdam, The Netherlands
*
Author for correspondence: Rolinda Drost, Helmholtz Research Institute, Experimental Psychology, Utrecht University, Heidelberglaan 1, 3584 CS Utrecht, The Netherlands. Tel.: +31 30 253 4281; Fax: +31 30 253 4511; E-mail: r.drost@propersona.nl

Abstract

Objective

Korsakoff’s syndrome (KS) is a chronic neuropsychiatric disorder characterised by severe anterograde amnesia and executive deficits. Theory of Mind (ToM) is the capacity to represent others’ mental states such as their knowledge, thoughts, feelings, beliefs, and intentions in order to explain and predict their behaviour. Surprisingly this topic has received hardly any attention in research on KS, although the severity of behavioural problems in KS suggest possible ToM difficulties. The aim of the present study was therefore to assess whether cognitive and affective ToM are impaired in patients with KS.

Methods

We examined 21 KS patients and 21 age- and gender-matched healthy controls on three standardised tests that assess cognitive and affective ToM, including the subtests of the mini-Social Cognition and Emotional Assessment battery and a specialised version of the Sally–Anne Test.

Results

KS patients showed largely impaired cognitive and affective ToM compared to healthy controls, as reflected in large effect sizes on both cognitive and affective ToM tests. Executive deficits explained problems in emotion recognition, but not other ToM aspects.

Conclusion

KS patients have large impairments in both cognitive and affective aspects of social cognition. Their ability to recognise emotions, take the perspective of others, and understand socially awkward situations is vastly compromised. The impairments in ToM functioning are to a large degree functionally discrepant from executive disorders that are commonly present in KS. This study therefore highlights the importance to properly index ToM functioning in neuropsychological assessments for individuals with a possible KS diagnosis.

Type
Original Article
Copyright
© Scandinavian College of Neuropsychopharmacology 2018 

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