At the regional level, by far the most prolific in terms of jurisprudence is the European Court of Human Rights: between its first judgment on the right to life in September 1995 and through late November 2020, 3,875 judgments concerned the right, of which 476 were issued by the Court’s Grand Chamber. But the Inter-American Court of Human Rights has also made a significant contribution to our understanding of the scope and legal status of the right to life, while the African Commission on Human and Peoples’ Rights brought together learning at the regional and global level in an important General Comment issued in 2015. A major gap in regional human rights protection exists across Asia and the Pacific.